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    dcp-66 Transcription factor dcp-66 [ Caenorhabditis elegans ]

    Gene ID: 172507, updated on 2-Nov-2024

    Summary

    Official Symbol
    dcp-66
    Official Full Name
    Transcription factor dcp-66
    Primary source
    WormBase:WBGene00000938
    Locus tag
    CELE_C26C6.5
    See related
    AllianceGenome:WB:WBGene00000938
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Enables DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in chromatin organization; mitochondrial unfolded protein response; and positive regulation of transcription by RNA polymerase II. Located in nucleus. Part of NuRD complex. Is expressed in body wall musculature; neurons; pharynx; and tail. Human ortholog(s) of this gene implicated in GAND syndrome. Orthologous to several human genes including GATAD2B (GATA zinc finger domain containing 2B). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

    See dcp-66 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    9
    Sequence:
    Chromosome: I; NC_003279.8 (7536104..7542159, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Guanine nucleotide-binding protein G(o) subunit alpha Neighboring gene Zinc metalloproteinase nas-36 Neighboring gene Nucleotide-diphospho-sugar transferase domain-containing protein Neighboring gene ncRNA Neighboring gene DUF4604 domain-containing protein

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    Transcription factor dcp-66
    NP_492111.3
    • Confirmed by transcript evidence
    NP_871831.3
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      7536104..7542159 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_182031.6NP_871831.3  Transcription factor dcp-66 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_871831.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      G5ECM2, G5ED89
    2. NM_059710.8NP_492111.3  Transcription factor dcp-66 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_492111.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5ECM2