Y39B6A.34 APOPT family protein Y39B6A.34, mitochondrial;COA8 family protein Y39B6A.34, mitochondrial [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: Y39B6A.34
Official Full Name: APOPT family protein Y39B6A.34, mitochondrial;COA8 family protein Y39B6A.34, mitochondrial
Primary source: WormBase:WBGene00012693
Locus tag: CELE_Y39B6A.34
See related: AllianceGenome:WB:WBGene00012693
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to be involved in intrinsic apoptotic signaling pathway. Predicted to be located in mitochondrial inner membrane. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in mitochondrial complex IV deficiency nuclear type 17. Orthologous to human COA8 (cytochrome c oxidase assembly factor 8). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See Y39B6A.34 in Genome Data Viewer

Location:: chromosome: V

Exon count:: 3

Sequence:: Chromosome: V; NC_003283.11 (19001018..19001856)

Chromosome V - NC_003283.11 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

Y39B6B.p (e-PCR)
- UniSTS:324600

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Process	Evidence Code	Pubs
involved_in apoptotic process	IEA Inferred from Electronic Annotation more info
involved_in intrinsic apoptotic signaling pathway	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in mitochondrial inner membrane	IEA Inferred from Electronic Annotation more info
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrion	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: APOPT family protein Y39B6A.34, mitochondrial;COA8 family protein Y39B6A.34, mitochondrial

NP_001263934.1

Confirmed by transcript evidence

NP_741663.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003283.11 Reference assembly

Range

19001018..19001856

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_171573.6 → NP_741663.1 COA8 family protein Y39B6A.34, mitochondrial [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_741663.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q8MYM9

Conserved Domains (1) summary

pfam10231
Location:18 → 137

DUF2315; Uncharacterized conserved protein (DUF2315)
NM_001277005.3 → NP_001263934.1 APOPT family protein Y39B6A.34, mitochondrial [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_001263934.1

Status: REVIEWED

UniProtKB/TrEMBL

J7SA57

Conserved Domains (1) summary

pfam10231
Location:1 → 28

DUF2315; Uncharacterized conserved protein (DUF2315)