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    mey morpheyus [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43715, updated on 9-Dec-2024

    Summary

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    Official Symbol
    meyprovided by FlyBase
    Official Full Name
    morpheyusprovided by FlyBase
    Primary source
    FLYBASE:FBgn0039851
    Locus tag
    Dmel_CG12063
    See related
    AllianceGenome:FB:FBgn0039851
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG12063; Dmel\CG12063
    Summary
    Involved in apical constriction and regulation of embryonic cell shape. Predicted to be located in membrane. Is expressed in several structures, including clypeo-labral primordium; dorsal epidermis primordium; embryonic epipharynx; epithelium; and gut section. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See mey in Genome Data Viewer
    Location:
    100C4-100C4; 3-102 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (31499235..31506992)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (27324957..27332714)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45555 Neighboring gene long non-coding RNA:CR45572 Neighboring gene long non-coding RNA:CR45573 Neighboring gene nyobe

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. nompA encodes a PNS-specific, ZP domain protein required to connect mechanosensory dendrites to sensory structures. Chung YD, et al. Neuron, 2001 Feb. PMID 11239432
    2. Regulation of smoothened by Drosophila G-protein-coupled receptor kinases. Cheng S, et al. Dev Biol, 2010 Jan 1. PMID 19850026, Free PMC Article
    3. A family of genes encoding zona pellucida (ZP) domain proteins is expressed in various epithelial tissues during Drosophila embryogenesis. Jaźwińska A, et al. Gene Expr Patterns, 2004 Jul. PMID 15183308
    4. Zona pellucida domain proteins remodel the apical compartment for localized cell shape changes. Fernandes I, et al. Dev Cell, 2010 Jan 19. PMID 20152178
    5. The Gene Expression Program for the Formation of Wing Cuticle in Drosophila. Sobala LF, et al. PLoS Genet, 2016 May. PMID 27232182, Free PMC Article

    See all (32) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in anatomical structure morphogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in apical constriction IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of embryonic cell shape IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    morpheyus
    Names
    CG12063-PA
    CG12063-PB
    mey-PA
    mey-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      31499235..31506992
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_143613.4 → NP_651870.3  morpheyus, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651870.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9V9X1
      Related
      FBpp0085151
      Conserved Domains (3) summary
      smart00241
      Location:408 → 642
      ZP; Zona pellucida (ZP) domain
      cd01099
      Location:233 → 311
      PAN_AP_HGF; Subfamily of PAN/APPLE-like domains; present in N-terminal (N) domains of plasminogen/hepatocyte growth factor proteins, and various proteins found in Bilateria, such as leech anti-platelet proteins. PAN/APPLE domains fulfill diverse biological functions ...
      pfam00024
      Location:146 → 223
      PAN_1; PAN domain

    2. NM_001300693.1 → NP_001287622.1  morpheyus, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001287622.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9V9X1
      Conserved Domains (3) summary
      smart00241
      Location:408 → 642
      ZP; Zona pellucida (ZP) domain
      cd01099
      Location:233 → 311
      PAN_AP_HGF; Subfamily of PAN/APPLE-like domains; present in N-terminal (N) domains of plasminogen/hepatocyte growth factor proteins, and various proteins found in Bilateria, such as leech anti-platelet proteins. PAN/APPLE domains fulfill diverse biological functions ...
      pfam00024
      Location:146 → 223
      PAN_1; PAN domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q960V7 Q960V7
    Q9V9X1 Q9V9X1

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