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    Or7a42 olfactory receptor family 7 subfamily A member 42 [ Mus musculus (house mouse) ]

    Gene ID: 18372, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Or7a42provided by MGI
    Official Full Name
    olfactory receptor family 7 subfamily A member 42provided by MGI
    Primary source
    MGI:MGI:107174
    See related
    Ensembl:ENSMUSG00000094080 AllianceGenome:MGI:107174
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Olfr8; MOR139-5P; GA_x5J8B7TNKDU-1250-1574
    Summary
    Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
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    Genomic context

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    See Or7a42 in Genome Data Viewer
    Location:
    10 C1; 10 39.72 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (78791041..78791973)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (78955207..78956139)

    Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 7 subfamily A member 39 Neighboring gene STARR-seq mESC enhancer starr_27236 Neighboring gene olfactory receptor family 7 subfamily A member 38 Neighboring gene STARR-seq mESC enhancer starr_27237 Neighboring gene olfactory receptor family 7 subfamily A member 37 Neighboring gene olfactory receptor family 7 subfamily A member 36

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Information coding in the olfactory system: evidence for a stereotyped and highly organized epitope map in the olfactory bulb. Ressler KJ, et al. Cell, 1994 Dec 30. PMID 7528109
    2. Olfactory receptors and signalling elements in the Grueneberg ganglion. Fleischer J, et al. J Neurochem, 2006 Jul. PMID 16805845
    3. Evolution of odorant receptors expressed in mammalian testes. Branscomb A, et al. Genetics, 2000 Oct. PMID 11014824, Free PMC Article
    4. The olfactory receptor gene repertoire in primates and mouse: evidence for reduction of the functional fraction in primates. Rouquier S, et al. Proc Natl Acad Sci U S A, 2000 Mar 14. PMID 10706615, Free PMC Article
    5. The chromosomal distribution of mouse odorant receptor genes. Sullivan SL, et al. Proc Natl Acad Sci U S A, 1996 Jan 23. PMID 8570653, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables olfactory receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables olfactory receptor activity ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within G protein-coupled receptor signaling pathway ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    involved_in detection of chemical stimulus involved in sensory perception of smell IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within sensory perception of smell ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    involved_in signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    olfactory receptor 7A42
    Names
    GA_x6K02T2QGN0-2857086-2856154
    odorant receptor M64
    olfactory receptor 8
    olfactory receptor GA_x5J8B7TNKDU-1250-1574

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_207201.1 → NP_997084.1  olfactory receptor 7A42

      See identical proteins and their annotated locations for NP_997084.1

      Status: PROVISIONAL

      Source sequence(s)
      AY318562
      Consensus CDS
      CCDS23971.1
      UniProtKB/Swiss-Prot
      Q60892, Q7TQV0, Q9ERY5, Q9JM18
      UniProtKB/TrEMBL
      Q9JHW3
      Related
      ENSMUSP00000080282.2, ENSMUST00000081571.2
      Conserved Domains (2) summary
      pfam00001
      Location:42 → 291
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:32 → 309
      7tm_4; Olfactory receptor

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000076.7 Reference GRCm39 C57BL/6J

      Range
      78791041..78791973
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NG_001635.2: Suppressed sequence

      Description
      NG_001635.2: This RefSeq was permanently suppressed because it is now thought that this gene does encode a protein.
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q60892.2 GenPept UniProtKB/Swiss-Prot:Q60892

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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