sfxn2 sideroflexin 2 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: sfxn2provided by ZNC
Official Full Name: sideroflexin 2provided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-2831
See related: Ensembl:ENSDARG00000017960 AllianceGenome:ZFIN:ZDB-GENE-040426-2831
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:55508; zgc:77081; wu:fa03a09
Summary: Predicted to enable transmembrane transporter activity. Predicted to be involved in serine import into mitochondrion. Predicted to act upstream of or within monoatomic ion transport and transmembrane transport. Predicted to be located in membrane and mitochondrion. Predicted to be active in mitochondrial inner membrane. Orthologous to human SFXN2 (sideroflexin 2). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 12

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	12	NC_007123.7 (33975182..33988888)
105	previous assembly	GRCz10 (GCF_000002035.5)	12	NC_007123.6 (33874144..33887902)

Chromosome 12 - NC_007123.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables monoatomic ion transmembrane transporter activity	IEA Inferred from Electronic Annotation more info
enables transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within monoatomic ion transport	IEA Inferred from Electronic Annotation more info
involved_in serine import into mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within transmembrane transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in mitochondrial inner membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrion	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: sideroflexin-2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_212730.1 → NP_997895.1 sideroflexin-2

See identical proteins and their annotated locations for NP_997895.1

Status: PROVISIONAL

Source sequence(s)

BC066638

UniProtKB/TrEMBL

A8E505, Q6NYD2

Related

ENSDARP00000036949.5, ENSDART00000036649.8

Conserved Domains (1) summary

pfam03820
Location:14 → 321

Mtc; Tricarboxylate carrier

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007123.7 Reference GRCz11 Primary Assembly

Range

33975182..33988888

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_021480030.2 → XP_021335705.1 sideroflexin-2 isoform X1

UniProtKB/TrEMBL

A8E505, Q6NYD2

Conserved Domains (1) summary

pfam03820
Location:14 → 321

Mtc; Tricarboxylate carrier
XM_005169471.5 → XP_005169528.1 sideroflexin-2 isoform X2

UniProtKB/TrEMBL

A0A8M2BGR6

Conserved Domains (1) summary

pfam03820
Location:43 → 310

Mtc; Tricarboxylate carrier