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    perR peroxide-responsive transcriptional repressor PerR [ Staphylococcus epidermidis ]

    Gene ID: 50018354, updated on 3-Dec-2024

    Summary

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    Gene symbol
    perR
    Gene description
    peroxide-responsive transcriptional repressor PerR
    Locus tag
    EQW00_RS04990
    Gene type
    protein coding
    Organism
    Staphylococcus epidermidis (strain: ATCC 14990, culture-collection: ATCC:14990, type-material: type strain of Staphylococcus epidermidis)
    Lineage
    Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae; Staphylococcus
    Old locus tag
    EQW00_04995
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    Genomic context

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    NZ_CP035288.1Genomic Context describing neighboring genes Neighboring gene phosphoglycerate dehydrogenase Neighboring gene thioredoxin-dependent thiol peroxidase Neighboring gene 16S ribosomal RNA Neighboring gene tRNA-Ile

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NZ_CP035288.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The roles of two O-donor ligands in the Fe(2+)-binding and H(2)O(2)-sensing by the Fe(2+)-dependent H(2)O(2) sensor PerR. Ji CJ, et al. Biochem Biophys Res Commun, 2018 Jun 22. PMID 29738773
    2. Staphylococcus aureus PerR Is a Hypersensitive Hydrogen Peroxide Sensor using Iron-mediated Histidine Oxidation. Ji CJ, et al. J Biol Chem, 2015 Aug 14. PMID 26134568, Free PMC Article
    3. Crystal structure of peroxide stress regulator from Streptococcus pyogenes provides functional insights into the mechanism of oxidative stress sensing. Makthal N, et al. J Biol Chem, 2013 Jun 21. PMID 23645680, Free PMC Article
    4. Regulation of perR expression by iron and PerR in Campylobacter jejuni. Kim M, et al. J Bacteriol, 2011 Nov. PMID 21908670, Free PMC Article
    5. MntR modulates expression of the PerR regulon and superoxide resistance in Staphylococcus aureus through control of manganese uptake. Horsburgh MJ, et al. Mol Microbiol, 2002 Jun. PMID 12028379

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    General protein information

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    Preferred Names
    peroxide-responsive transcriptional repressor PerR

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NZ_CP035288.1 Reference assembly

      Range
      1019489..1019941
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. WP_001830391.1 MULTISPECIES: peroxide-responsive transcriptional repressor PerR [Staphylococcus]

      See identical proteins and their annotated locations for WP_001830391.1

      UniProtKB/Swiss-Prot
      Q5HN74, Q8CNQ7
      UniProtKB/TrEMBL
      A0A2G7HXG6, A0A9Q5JN55, A0AAV3DAP9
      Conserved Domains (1) summary
      COG0735
      Location:10 → 148
      Fur; Fe2+ or Zn2+ uptake regulation protein [Inorganic ion transport and metabolism]
    Nucleotide Protein
    Heading Accession and Version

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