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    bluB 5,6-dimethylbenzimidazole synthase [ Cutibacterium acnes subsp. acnes ]

    Gene ID: 92856917, updated on 3-Dec-2024

    Summary

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    Gene symbol
    bluB
    Gene description
    5,6-dimethylbenzimidazole synthase
    Locus tag
    FNX46_RS05110
    Gene type
    protein coding
    Organism
    Cutibacterium acnes subsp. acnes (strain: NBRC 107605, sub-species: acnes, culture-collection: NBRC:107605, type-material: type strain of Cutibacterium acnes)
    Lineage
    Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales; Propionibacteriaceae; Cutibacterium
    Old locus tag
    CacPP4_09180
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    Genomic context

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    NZ_AP019723.1Genomic Context describing neighboring genes Neighboring gene succinate dehydrogenase cytochrome b subunit Neighboring gene fumarate reductase/succinate dehydrogenase flavoprotein subunit Neighboring gene succinate dehydrogenase/fumarate reductase iron-sulfur subunit Neighboring gene tRNA dihydrouridine synthase DusB Neighboring gene HD domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NZ_AP019723.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. BluB cannibalizes flavin to form the lower ligand of vitamin B12. Taga ME, et al. Nature, 2007 Mar 22. PMID 17377583, Free PMC Article
    2. Single-enzyme conversion of FMNH2 to 5,6-dimethylbenzimidazole, the lower ligand of B12. Gray MJ, et al. Proc Natl Acad Sci U S A, 2007 Feb 20. PMID 17301238, Free PMC Article
    3. Comparative genomics of the vitamin B12 metabolism and regulation in prokaryotes. Rodionov DA, et al. J Biol Chem, 2003 Oct 17. PMID 12869542
    4. Identification and sequence analysis of genes involved in late steps in cobalamin (vitamin B12) synthesis in Rhodobacter capsulatus. Pollich M, et al. J Bacteriol, 1995 Aug. PMID 7635831, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General protein information

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    Preferred Names
    5,6-dimethylbenzimidazole synthase
    WP_002515596.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NZ_AP019723.1 Reference assembly

      Range
      1010526..1012292 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. WP_002515596.1 MULTISPECIES: 5,6-dimethylbenzimidazole synthase [Cutibacterium]

      See identical proteins and their annotated locations for WP_002515596.1

      UniProtKB/TrEMBL
      A0AAD0QUH0, Q6A960
    Nucleotide Protein
    Heading Accession and Version