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    guaB IMP dehydrogenase [ Streptococcus pyogenes ]

    Gene ID: 69901624, updated on 15-Dec-2024

    Summary

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    Gene symbol
    guaB
    Gene description
    IMP dehydrogenase
    Locus tag
    DQM35_RS08830
    Gene type
    protein coding
    Organism
    Streptococcus pyogenes (strain: NCTC12064, serovar: Lancefield Group A, culture-collection: NCTC:12064)
    Lineage
    Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus
    Old locus tag
    NCTC12064_01736
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    Genomic context

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    Location:
    chromosome: 1

    1 - NZ_LS483338.1Genomic Context describing neighboring genes Neighboring gene DNA replication/repair protein RecF Neighboring gene GRP family sugar transporter Neighboring gene tryptophan--tRNA ligase Neighboring gene YitT family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NZ_LS483338.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Two classes of bacterial IMPDHs according to their quaternary structures and catalytic properties. Alexandre T, et al. PLoS One, 2015. PMID 25706619, Free PMC Article
    2. The CBS subdomain of inosine 5'-monophosphate dehydrogenase regulates purine nucleotide turnover. Pimkin M, et al. Mol Microbiol, 2008 Apr. PMID 18312263, Free PMC Article
    3. Characteristics and crystal structure of bacterial inosine-5'-monophosphate dehydrogenase. Zhang R, et al. Biochemistry, 1999 Apr 13. PMID 10200156

    GeneRIFs: Gene References Into Functions

    General protein information

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    Preferred Names
    IMP dehydrogenase
    WP_002991454.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NZ_LS483338.1 Reference assembly

      Range
      1732663..1734144 complement
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      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. WP_002991454.1 IMP dehydrogenase [Streptococcus pyogenes]

      See identical proteins and their annotated locations for WP_002991454.1

      UniProtKB/Swiss-Prot
      P0C0H6, P0C0H7, P50099, P68838, P68839, Q48W00, Q5X9A3
      UniProtKB/TrEMBL
      A0A0H3C114, A0A4U7I561, Q1JJB8, Q48QL0, U2TX64
      Conserved Domains (1) summary
      PRK05567
      Location:5 → 493
      PRK05567; inosine 5'-monophosphate dehydrogenase; Reviewed
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P0C0H6.2

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