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    pmrA two-component system response regulator PmrA [ Citrobacter freundii ]

    Gene ID: 87003078, updated on 3-Dec-2024

    Summary

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    Gene symbol
    pmrA
    Gene description
    two-component system response regulator PmrA
    Locus tag
    JMV71_RS21525
    Gene type
    protein coding
    Organism
    Citrobacter freundii (strain: MSB1_1H, isolate: MSB1_1H, nat-host: Homo sapiens)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Citrobacter; Citrobacter freundii complex
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    Genomic context

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    Location:
    chromosome: 1

    1 - NZ_LR890181.1Genomic Context describing neighboring genes Neighboring gene arginine/agmatine antiporter Neighboring gene phosphoethanolamine transferase EptA Neighboring gene two-component system sensor histidine kinase PmrB Neighboring gene LpxT activity modulator PmrR Neighboring gene glycine betaine/L-proline transporter ProP

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NZ_LR890181.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Structural basis of a physical blockage mechanism for the interaction of response regulator PmrA with connector protein PmrD from Klebsiella pneumoniae. Luo SC, et al. J Biol Chem, 2013 Aug 30. PMID 23861396, Free PMC Article
    2. The Salmonella PmrAB regulon: lipopolysaccharide modifications, antimicrobial peptide resistance and more. Gunn JS. Trends Microbiol, 2008 Jun. PMID 18467098
    3. PmrA-PmrB-regulated genes necessary for 4-aminoarabinose lipid A modification and polymyxin resistance. Gunn JS, et al. Mol Microbiol, 1998 Mar. PMID 9570402
    4. Novel regulation targets of the metal-response BasS-BasR two-component system of Escherichia coli. Ogasawara H, et al. Microbiology (Reading), 2012 Jun. PMID 22442305
    5. A genomic epidemiological study shows that prevalence of antimicrobial resistance in Enterobacterales is associated with the livestock host, as well as antimicrobial usage. AbuOun M, et al. Microb Genom, 2021 Oct. PMID 34609275, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General protein information

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    Preferred Names
    two-component system response regulator PmrA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NZ_LR890181.1 Reference assembly

      Range
      4460798..4461466
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      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. WP_003031849.1 MULTISPECIES: two-component system response regulator PmrA [Citrobacter]

      See identical proteins and their annotated locations for WP_003031849.1

      UniProtKB/TrEMBL
      A0A0D7LBL4, A0A0J1MSL1, A0A212I7I3, A0A9X1G1A7, A0AAW7F680, A0AAW7FYJ4, A0AAW7G565
    Nucleotide Protein
    Heading Accession and Version