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    MCAN_RS11525 polyadenylate-specific 3'-exoribonuclease AS [ Mycobacterium canettii CIPT 140010059 ]

    Gene ID: 45426155, updated on 11-Dec-2024

    Summary

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    Gene symbol
    MCAN_RS11525
    Gene description
    polyadenylate-specific 3'-exoribonuclease AS
    Locus tag
    MCAN_RS11525
    Gene type
    protein coding
    Organism
    Mycobacterium canettii CIPT 140010059 (strain: CIPT 140010059)
    Lineage
    Bacteria; Bacillati; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
    Old locus tag
    MCAN_22011
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    Genomic context

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    Sequence:
    NC_015848.1 (2494479..2494985, complement)

    NC_015848.1Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene class II 3-deoxy-7-phosphoheptulonate synthase Neighboring gene integral membrane protein Neighboring gene alpha-(1-2)-phosphatidylinositol mannoside mannosyltransferase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_015848.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Structure and Function of RNase AS: A Novel Virulence Factor From Mycobacterium tuberculosis. Romano M, et al. Curr Med Chem, 2015. PMID 25882544
    2. Structure and function of RNase AS, a polyadenylate-specific exoribonuclease affecting mycobacterial virulence in vivo. Romano M, et al. Structure, 2014 May 6. PMID 24704253
    3. Mycobacterium tuberculosis Rv2179c protein establishes a new exoribonuclease family with broad phylogenetic distribution. Abendroth J, et al. J Biol Chem, 2014 Jan 24. PMID 24311791, Free PMC Article
    4. Genomic analysis of smooth tubercle bacilli provides insights into ancestry and pathoadaptation of Mycobacterium tuberculosis. Supply P, et al. Nat Genet, 2013 Feb. PMID 23291586, Free PMC Article
    5. The genome of Mycobacterium africanum West African 2 reveals a lineage-specific locus and genome erosion common to the M. tuberculosis complex. Bentley SD, et al. PLoS Negl Trop Dis, 2012. PMID 22389744, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    General protein information

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    Preferred Names
    polyadenylate-specific 3'-exoribonuclease AS

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_015848.1 Reference assembly

      Range
      2494479..2494985 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. WP_003411331.1 MULTISPECIES: polyadenylate-specific 3'-exoribonuclease AS [Mycobacterium]

      See identical proteins and their annotated locations for WP_003411331.1

      UniProtKB/Swiss-Prot
      F2GJZ2, I6Y8M5, L7N5T0, O53513, P9WJ72, P9WJ73, Q7D7E6
      UniProtKB/TrEMBL
      A0A045JQ63, A0A0H3LB18, A0A0H3M7X6, A0A1R3Y0H1, A0A7V9WGX7, A0A829CDA4, A0A9P2H8Q3, A0AAU0Q613, A0AAW8HWH8, A0AAX1PUM1, A5U4K6
      Conserved Domains (1) summary
      NF033638
      Location:3 → 156
      RNase_AS; polyadenylate-specific 3'-exoribonuclease AS
    Nucleotide Protein
    Heading Accession and Version

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