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    cobA uroporphyrinogen-III C-methyltransferase [ Mycobacterium canettii CIPT 140010059 ]

    Gene ID: 45426834, updated on 11-Dec-2024

    Summary

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    Gene symbol
    cobA
    Gene description
    uroporphyrinogen-III C-methyltransferase
    Locus tag
    MCAN_RS15080
    Gene type
    protein coding
    Organism
    Mycobacterium canettii CIPT 140010059 (strain: CIPT 140010059)
    Lineage
    Bacteria; Bacillati; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
    Old locus tag
    MCAN_28691
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    Genomic context

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    Sequence:
    NC_015848.1 (3213288..3214505, complement)

    NC_015848.1Genomic Context describing neighboring genes Neighboring gene proline--tRNA ligase Neighboring gene multidrug efflux MFS transporter EfpA Neighboring gene cobyrinate a,c-diamide synthase Neighboring gene cob(I)yrinic acid a,c-diamide adenosyltransferase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_015848.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genomic analysis of smooth tubercle bacilli provides insights into ancestry and pathoadaptation of Mycobacterium tuberculosis. Supply P, et al. Nat Genet, 2013 Feb. PMID 23291586, Free PMC Article
    2. The genome of Mycobacterium africanum West African 2 reveals a lineage-specific locus and genome erosion common to the M. tuberculosis complex. Bentley SD, et al. PLoS Negl Trop Dis, 2012. PMID 22389744, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    General protein information

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    Preferred Names
    uroporphyrinogen-III C-methyltransferase
    WP_003414535.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_015848.1 Reference assembly

      Range
      3213288..3214505 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. WP_003414535.1 MULTISPECIES: uroporphyrinogen-III C-methyltransferase [Mycobacterium]

      See identical proteins and their annotated locations for WP_003414535.1

      UniProtKB/TrEMBL
      A0A045IEG0, A0A0H3LH47, A0A0H3M9R7, A0A1R3Y2D0, A0A829C1S6, A0A9P2HAM0, A0AAU0Q610, A0AAW8I6L6, A0AAX1PSC2, A5U6J9, F2GL86, I6X5I7, P95077, Q7D6G7
      Conserved Domains (2) summary
      COG1648
      Location:24 → 152
      CysG2; Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain) [Coenzyme transport and metabolism]
      cd11642
      Location:165 → 394
      SUMT; Uroporphyrin-III C-methyltransferase (also known as S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT)
    Nucleotide Protein
    Heading Accession and Version

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