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    ptsA putative PTS multiphosphoryl transfer protein PtsA [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948437, updated on 17-Dec-2024

    Summary

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    Official Symbol
    ptsA
    Official Full Name
    putative PTS multiphosphoryl transfer protein PtsA
    Primary source
    ECOCYC:EG11906
    Locus tag
    b3947
    See related
    ASAP:ABE-0012920
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3939; frwA; pt1A; yijH
    Summary
    ptsA encodes a fused Enzyme I-IIAFru of the sugar phosphotransferase system . [More information is available at EcoCyc: EG11906].
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    Genomic context

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    Sequence:
    NC_000913.3 (4139720..4142221, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene L-1,2-propanediol dehydrogenase/glycerol dehydrogenase Neighboring gene fructose-6-phosphate aldolase 2 Neighboring gene putative PTS enzyme IIC component FrwC Neighboring gene putative PTS enzyme IIB component FrwB

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Stationary-phase quorum-sensing signals affect autoinducer-2 and gene expression in Escherichia coli. Ren D, et al. Appl Environ Microbiol, 2004 Apr. PMID 15066794, Free PMC Article
    2. Novel phosphotransferase system genes revealed by bacterial genome analysis--a gene cluster encoding a unique Enzyme I and the proteins of a fructose-like permease system. Reizer J, et al. Microbiology (Reading), 1995 Apr. PMID 7773398
    3. Analysis of the Escherichia coli genome. IV. DNA sequence of the region from 89.2 to 92.8 minutes. Blattner FR, et al. Nucleic Acids Res, 1993 Nov 25. PMID 8265357, Free PMC Article
    4. Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110. Hayashi K, et al. Mol Syst Biol, 2006. PMID 16738553, Free PMC Article
    5. The complete genome sequence of Escherichia coli K-12. Blattner FR, et al. Science, 1997 Sep 5. PMID 9278503

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phosphoenolpyruvate-protein phosphotransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables phosphoenolpyruvate-protein phosphotransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transferase activity, transferring phosphorus-containing groups IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in N-acetylglucosamine transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in fructose import across plasma membrane NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in phosphoenolpyruvate-dependent sugar phosphotransferase system IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in phosphoenolpyruvate-dependent sugar phosphotransferase system NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of transmembrane transporter complex NAS
    Non-traceable Author Statement
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    putative PTS multiphosphoryl transfer protein PtsA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      4139720..4142221 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. YP_026278.1 putative PTS multiphosphoryl transfer protein PtsA [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for YP_026278.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A785ESZ8
      Conserved Domains (3) summary
      COG1080
      Location:123 → 685
      PtsA; Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]
      COG1762
      Location:689 → 832
      PtsN; Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) [Carbohydrate transport and metabolism, Signal transduction mechanisms]
      COG1925
      Location:2 → 91
      PtsH; Phosphotransferase system, HPr and related phosphotransfer proteins [Signal transduction mechanisms, Carbohydrate transport and metabolism]
    Nucleotide Protein
    Heading Accession and Version

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