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    carnmt1 carnosine N-methyltransferase 1 [ Danio rerio (zebrafish) ]

    Gene ID: 503765, updated on 27-Dec-2024

    Summary

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    Official Symbol
    carnmt1provided by ZNC
    Official Full Name
    carnosine N-methyltransferase 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050306-48
    See related
    Ensembl:ENSDARG00000102865 AllianceGenome:ZFIN:ZDB-GENE-050306-48
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    wu:fj43d04; zgc:112985
    Summary
    Predicted to enable carnosine N-methyltransferase activity. Predicted to act upstream of or within methylation. Orthologous to human CARNMT1 (carnosine N-methyltransferase 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See carnmt1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (25300990..25309551)
    105 previous assembly GRCz10 (GCF_000002035.5) Unplaced Scaffold NW_003334369.1 (41269..49830, complement)

    Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101882330 Neighboring gene uncharacterized LOC103910306 Neighboring gene wu:fa19b12 Neighboring gene transient receptor potential cation channel, subfamily M, member 6 Neighboring gene uncharacterized LOC110439811

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. The zebrafish retinoid-related orphan receptor (ror) gene family. Flores MV, et al. Gene Expr Patterns, 2007 Apr. PMID 17374568
    2. Consequences of lineage-specific gene loss on functional evolution of surviving paralogs: ALDH1A and retinoic acid signaling in vertebrate genomes. Cañestro C, et al. PLoS Genet, 2009 May. PMID 19478994, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables S-adenosylmethionine-dependent methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables carnosine N-methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within methylation IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    carnosine N-methyltransferase
    NP_001013361.1
    XP_005171825.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001013343.2 → NP_001013361.1  carnosine N-methyltransferase

      See identical proteins and their annotated locations for NP_001013361.1

      Status: PROVISIONAL

      Source sequence(s)
      BC090679
      UniProtKB/TrEMBL
      A0A8M3AQU6, Q5CZW3
      Related
      ENSDARP00000131741.1, ENSDART00000163425.2
      Conserved Domains (1) summary
      pfam07942
      Location:13 → 277
      N2227; N2227-like protein

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007116.7 Reference GRCz11 Primary Assembly

      Range
      25300990..25309551
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005171768.5 → XP_005171825.1  carnosine N-methyltransferase isoform X1

      UniProtKB/TrEMBL
      A0A8M2BJ21
      Conserved Domains (1) summary
      pfam07942
      Location:118 → 382
      N2227; N2227-like protein
    Nucleotide Protein Strain
    Heading Accession and Version

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