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    hpxO FAD-dependent urate hydroxylase HpxO [ Klebsiella quasipneumoniae ]

    Gene ID: 93253966, updated on 12-Dec-2024

    Summary

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    Gene symbol
    hpxO
    Gene description
    FAD-dependent urate hydroxylase HpxO
    Locus tag
    LA349_RS25425
    Gene type
    protein coding
    Organism
    Klebsiella quasipneumoniae (strain: FDAARGOS_1503, culture-collection: DSM:28211, type-material: type strain of Klebsiella quasipneumoniae)
    Lineage
    Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella
    Old locus tag
    LA349_25425
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    Genomic context

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    NZ_CP083633.1Genomic Context describing neighboring genes Neighboring gene MFS transporter Neighboring gene molybdenum cofactor-independent xanthine hydroxylase subunit HpxE Neighboring gene molybdenum cofactor-independent xanthine hydroxylase subunit HpxD Neighboring gene LysR family hpxDE operon transcriptional regulator HpxR Neighboring gene nucleobase:cation symporter-2 family protein Neighboring gene 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase Neighboring gene hydroxyisourate hydrolase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NZ_CP083633.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Structural and mechanistic studies of HpxO, a novel flavin adenine dinucleotide-dependent urate oxidase from Klebsiella pneumoniae. Hicks KA, et al. Biochemistry, 2013 Jan 22. PMID 23259842, Free PMC Article
    2. Biochemical characterization of the HpxO enzyme from Klebsiella pneumoniae, a novel FAD-dependent urate oxidase. O'Leary SE, et al. Biochemistry, 2009 Apr 14. PMID 19260710, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General protein information

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    Preferred Names
    FAD-dependent urate hydroxylase HpxO

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NZ_CP083633.1 Reference assembly

      Range
      5316785..5317939 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. WP_023289663.1 MULTISPECIES: FAD-dependent urate hydroxylase HpxO [Klebsiella]

      See identical proteins and their annotated locations for WP_023289663.1

      UniProtKB/TrEMBL
      A0AAI8ISG4, A0AAN2CDX4
    Nucleotide Protein
    Heading Accession and Version