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    Prss39 protease, serine, 39 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 363215, updated on 9-Dec-2024

    Summary

    Symbol
    Prss39provided by RGD
    Full Name
    protease, serine, 39provided by RGD
    Primary source
    RGD:1309276
    See related
    EnsemblRapid:ENSRNOG00000023858 AllianceGenome:RGD:1309276
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Tesp1; Tesp2; Prss40
    Summary
    Predicted to be located in acrosomal vesicle. Orthologous to human PRSS40B (serine protease 40B (pseudogene)). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 110.3), Spleen (RPKM 31.9) and 2 other tissues See more
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    Genomic context

    See Prss39 in Genome Data Viewer
    Location:
    9q21
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 9 NC_086027.1 (44190959..44208923)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 9 NC_051344.1 (36695037..36713004)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (40999027..41012607)

    Chromosome 9 - NC_086027.1Genomic Context describing neighboring genes Neighboring gene coiled-coil domain containing 115 Neighboring gene IMP U3 small nucleolar ribonucleoprotein 4 Neighboring gene protein tyrosine phosphatase, non-receptor type 18 Neighboring gene uncharacterized LOC134480354 Neighboring gene cripto, FRL-1, cryptic family 1 Neighboring gene small nucleolar RNA, H/ACA box 51 Neighboring gene protease, serine, 40

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General protein information

    Preferred Names
    serine protease 40
    Names
    serine protease 40-like
    testicular serine protease 1
    testicular serine protease 2
    NP_001013244.1
    XP_006244779.1
    XP_006244780.1
    XP_017451998.1
    XP_038939762.1
    XP_038939763.1
    XP_038939764.1
    XP_038939765.1
    XP_038939766.1
    XP_063123435.1
    XP_063123436.1
    XP_063123437.1
    XP_063123438.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001013226.1NP_001013244.1  serine protease 40 precursor

      See identical proteins and their annotated locations for NP_001013244.1

      Status: PROVISIONAL

      Source sequence(s)
      BC079254
      UniProtKB/Swiss-Prot
      Q6AXZ6
      Related
      ENSRNOP00000038053.3, ENSRNOT00000034214.6
      Conserved Domains (1) summary
      cd00190
      Location:70312
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086027.1 Reference GRCr8

      Range
      44190959..44208923
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039083834.1XP_038939762.1  serine protease 40 isoform X3

      Conserved Domains (1) summary
      cd00190
      Location:18260
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    2. XM_017596509.2XP_017451998.1  serine protease 40 isoform X3

      Conserved Domains (1) summary
      cd00190
      Location:18260
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    3. XM_039083836.2XP_038939764.1  serine protease 40 isoform X6

      Conserved Domains (1) summary
      cd00190
      Location:72202
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    4. XM_039083838.2XP_038939766.1  serine protease 40 isoform X9

      Conserved Domains (1) summary
      cd00190
      Location:72202
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    5. XM_039083835.2XP_038939763.1  serine protease 40 isoform X4

      Conserved Domains (1) summary
      cd00190
      Location:72265
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    6. XM_006244717.5XP_006244779.1  serine protease 40 isoform X1

      Related
      ENSRNOP00000107426.1, ENSRNOT00000148729.1
      Conserved Domains (2) summary
      smart00020
      Location:71311
      Tryp_SPc; Trypsin-like serine protease
      cd00190
      Location:72314
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    7. XM_063267368.1XP_063123438.1  serine protease 40 isoform X11

      UniProtKB/TrEMBL
      A6INA4
    8. XM_006244718.5XP_006244780.1  serine protease 40 isoform X2

      UniProtKB/TrEMBL
      A0A0G2K0I9
      Conserved Domains (2) summary
      smart00020
      Location:49289
      Tryp_SPc; Trypsin-like serine protease
      cd00190
      Location:50292
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    9. XM_063267365.1XP_063123435.1  serine protease 40 isoform X5

    10. XM_063267367.1XP_063123437.1  serine protease 40 isoform X10

      UniProtKB/TrEMBL
      A6INA4
    11. XM_063267366.1XP_063123436.1  serine protease 40 isoform X7

      UniProtKB/TrEMBL
      A6INA4
    12. XM_039083837.2XP_038939765.1  serine protease 40 isoform X8

      Conserved Domains (1) summary
      cd00190
      Location:4173
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...