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    Sp140l1 Sp140 nuclear body protein like 1 [ Mus musculus (house mouse) ]

    Gene ID: 381287, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Sp140l1provided by MGI
    Official Full Name
    Sp140 nuclear body protein like 1provided by MGI
    Primary source
    MGI:MGI:3037746
    See related
    Ensembl:ENSMUSG00000089844 AllianceGenome:MGI:3037746
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm1888; A530032D15Rik
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in fibrillar center and mitochondrion. Predicted to be active in nucleus. Orthologous to human SP140 (SP140 nuclear body protein). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Broad expression in spleen adult (RPKM 3.6), mammary gland adult (RPKM 1.5) and 20 other tissues See more
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    Genomic context

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    See Sp140l1 in Genome Data Viewer
    Location:
    1 C5; 1 43.44 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (85065860..85088016, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (85088139..85110297, complement)

    Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene Sp140 nuclear body protein pseudogene Neighboring gene Sp140 nuclear body protein pseudogene Neighboring gene RIKEN cDNA A530040E14 gene Neighboring gene STARR-seq mESC enhancer starr_01538 Neighboring gene STARR-seq mESC enhancer starr_01539 Neighboring gene Sp140 nuclear body protein pseudogene Neighboring gene STARR-seq mESC enhancer starr_01540 Neighboring gene STARR-seq mESC enhancer starr_01541 Neighboring gene predicted gene, 38510 Neighboring gene predicted gene, 53253 Neighboring gene STARR-seq mESC enhancer starr_01543 Neighboring gene predicted gene, 53568

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    2. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
    3. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article
    4. Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. Carninci P, et al. Genome Res, 2000 Oct. PMID 11042159, Free PMC Article
    5. Functional annotation of a full-length mouse cDNA collection. Kawai J, et al. Nature, 2001 Feb 8. PMID 11217851

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Clone Names

    • MGC130185, MGC130186

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in fibrillar center ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    SP140 nuclear body protein family member

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_213615.2 → NP_998780.2  SP140 nuclear body protein family member

      Status: VALIDATED

      Source sequence(s)
      AC167036, AK040872
      Consensus CDS
      CCDS15107.1
      UniProtKB/TrEMBL
      E9PV05, Q8BS13
      Related
      ENSMUSP00000125122.2, ENSMUST00000160792.8
      Conserved Domains (1) summary
      pfam03172
      Location:28 → 119
      Sp100; Sp100 domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000067.7 Reference GRCm39 C57BL/6J

      Range
      85065860..85088016 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017321386.3 → XP_017176875.1  SP140 nuclear body protein family member isoform X3

      UniProtKB/TrEMBL
      Q8BS13
      Conserved Domains (1) summary
      pfam03172
      Location:39 → 133
      HSR; HSR domain

    2. XM_006496502.5 → XP_006496565.1  SP140 nuclear body protein family member isoform X2

      Conserved Domains (1) summary
      pfam03172
      Location:25 → 119
      HSR; HSR domain

    3. XM_017321384.3 → XP_017176873.1  SP140 nuclear body protein family member isoform X1

      Conserved Domains (1) summary
      pfam03172
      Location:41 → 135
      HSR; HSR domain
    Nucleotide Protein Strain
    Heading Accession and Version

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