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    Dbp D site albumin promoter binding protein [ Mus musculus (house mouse) ]

    Gene ID: 13170, updated on 27-Nov-2024

    Summary

    Official Symbol
    Dbpprovided by MGI
    Official Full Name
    D site albumin promoter binding proteinprovided by MGI
    Primary source
    MGI:MGI:94866
    See related
    Ensembl:ENSMUSG00000059824 AllianceGenome:MGI:94866
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    The protein encoded by this gene is a member of the Par bZIP transcription factor family and binds to specific sequences in the promoters of several genes, such as albumin, Cyp2a4, and Cyp2a5. The encoded protein can bind DNA as a homo- or heterodimer and is involved in the regulation of some circadian rhythym genes. [provided by RefSeq, Feb 2014]
    Expression
    Biased expression in adrenal adult (RPKM 215.0), bladder adult (RPKM 83.9) and 10 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Dbp in Genome Data Viewer
    Location:
    7 B3; 7 29.45 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (45354658..45359579)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (45705100..45710203)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene secretory blood group 1 Neighboring gene netrin 5 Neighboring gene carbonic anhydrase 11 Neighboring gene STARR-positive B cell enhancer ABC_E350 Neighboring gene sphingosine kinase 2 Neighboring gene STARR-positive B cell enhancer ABC_E6545 Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:52973256-52973443 Neighboring gene ribosomal protein L18 Neighboring gene family with sequence similarity 83, member E Neighboring gene sperm acrosome associated 4

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (5) 
    • Targeted (2)  1 citation

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Component Evidence Code Pubs
    part_of RNA polymerase II transcription regulator complex IEA
    Inferred from Electronic Annotation
    more info
     
    part_of RNA polymerase II transcription regulator complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm TAS
    Traceable Author Statement
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    D site-binding protein
    Names
    albumin D box-binding protein
    albumin D-element-binding protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001412312.1NP_001399241.1  D site-binding protein isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC167242
      UniProtKB/TrEMBL
      A0A1B0GS46
      Related
      ENSMUSP00000147790.2, ENSMUST00000211513.2
    2. NM_001412313.1NP_001399242.1  D site-binding protein isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC167242
      UniProtKB/TrEMBL
      Q5XFZ5
    3. NM_016974.4NP_058670.2  D site-binding protein isoform 1

      See identical proteins and their annotated locations for NP_058670.2

      Status: VALIDATED

      Source sequence(s)
      AC167242
      Consensus CDS
      CCDS21260.1
      UniProtKB/Swiss-Prot
      Q60925, Q8VCX3
      UniProtKB/TrEMBL
      Q3USN7
      Related
      ENSMUSP00000079693.4, ENSMUST00000080885.12
      Conserved Domains (1) summary
      cd14695
      Location:254313
      bZIP_HLF; Basic leucine zipper (bZIP) domain of Hepatic leukemia factor (HLF) and similar proteins: a DNA-binding and dimerization domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      45354658..45359579
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006540597.2XP_006540660.1  D site-binding protein isoform X2

      Conserved Domains (1) summary
      cd14695
      Location:117176
      bZIP_HLF; Basic leucine zipper (bZIP) domain of Hepatic leukemia factor (HLF) and similar proteins: a DNA-binding and dimerization domain