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    CG4119 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 31481, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG4119provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0028474
    Locus tag
    Dmel_CG4119
    See related
    AllianceGenome:FB:FBgn0028474
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA.LD23634; BcDNA:LD23634; cg4119; Dmel\CG4119
    Summary
    Predicted to enable mRNA binding activity. Involved in regulation of alternative mRNA splicing, via spliceosome. Part of precatalytic spliceosome. Is expressed in organism and spermatozoon. Orthologous to human RBM25 (RNA binding motif protein 25). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG4119 in Genome Data Viewer
    Location:
    5A10-5A11; 1-12 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (5666052..5670652)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (5560085..5564685)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene Otopetrin-like c Neighboring gene antisense RNA:CR45520 Neighboring gene Sirtuin 4 Neighboring gene Rab18 Neighboring gene Ribosomal protein L35

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Direct measurement of pervasive weak repression by microRNAs and their role at the network level. Ma F, et al. BMC Genomics, 2018 May 15. PMID 29764374, Free PMC Article
    2. Reagent and Data Resources for Investigation of RNA Binding Protein Functions in Drosophila melanogaster Cultured Cells. Mohr SE, et al. G3 (Bethesda), 2015 Jul 21. PMID 26199285, Free PMC Article
    3. Genomic organization of gypsy chromatin insulators in Drosophila melanogaster. Ramos E, et al. Genetics, 2006 Apr. PMID 16452134, Free PMC Article
    4. Identification of alternative splicing regulators by RNA interference in Drosophila. Park JW, et al. Proc Natl Acad Sci U S A, 2004 Nov 9. PMID 15492211, Free PMC Article
    5. A genetic screen for suppressors of Drosophila NSF2 neuromuscular junction overgrowth. Laviolette MJ, et al. Genetics, 2005 Jun. PMID 15834148, Free PMC Article

    See all (36) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables mRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables mRNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mRNA splicing, via spliceosome IC
    Inferred by Curator
    more info
    		 PubMed 
    involved_in regulation of alternative mRNA splicing, via spliceosome HMP PubMed 
    involved_in regulation of alternative mRNA splicing, via spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IC
    Inferred by Curator
    more info
    		 PubMed 
    part_of precatalytic spliceosome HDA PubMed 

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG4119-PA
    CG4119-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      5666052..5670652
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001297970.1 → NP_001284899.1  uncharacterized protein Dmel_CG4119, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001284899.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9V3Y5
      Conserved Domains (2) summary
      smart00311
      Location:917 → 988
      PWI; PWI, domain in splicing factors
      cd12446
      Location:62 → 136
      RRM_RBM25; RNA recognition motif in eukaryotic RNA-binding protein 25 and similar proteins

    2. NM_132014.3 → NP_572242.1  uncharacterized protein Dmel_CG4119, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_572242.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9V3Y5
      Related
      FBpp0070765
      Conserved Domains (2) summary
      smart00311
      Location:917 → 988
      PWI; PWI, domain in splicing factors
      cd12446
      Location:62 → 136
      RRM_RBM25; RNA recognition motif in eukaryotic RNA-binding protein 25 and similar proteins
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9V3Y5 Q9V3Y5

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