Tenm2 teneurin transmembrane protein 2 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Tenm2provided by MGI
Official Full Name: teneurin transmembrane protein 2provided by MGI
Primary source: MGI:MGI:1345184
See related: Ensembl:ENSMUSG00000049336 AllianceGenome:MGI:1345184
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Odz2; Odz3; Ten-2; Ten-m2
Summary: Enables protein heterodimerization activity and protein homodimerization activity. Predicted to be involved in several processes, including heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; positive regulation of filopodium assembly; and retrograde trans-synaptic signaling by trans-synaptic protein complex. Predicted to be located in several cellular components, including PML body; dendritic spine; and postsynaptic membrane. Predicted to be active in glutamatergic synapse and neuron projection. Predicted to be extrinsic component of postsynaptic membrane. Is expressed in several structures, including alimentary system; integumental system; nervous system; sensory organ; and skeleton. Orthologous to human TENM2 (teneurin transmembrane protein 2). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in CNS E18 (RPKM 3.0), whole brain E14.5 (RPKM 2.9) and 8 other tissues See more
Orthologs: human all
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Genomic context

Location:: 11 A4- A5; 11 21.96 cM

Exon count:: 43

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	11	NC_000077.7 (35897483..37881486, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	11	NC_000077.6 (36006656..37237053, complement)

Chromosome 11 - NC_000077.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

These data demonstrate a requirement for Ten-m2 in the establishment of ipsilateral projections, and thus the generation of binocular circuits, critical for mammalian visual function.
Title: Ten-m2 is required for the generation of binocular visual circuits.

Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (1)
Targeted (1) 1 citation

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

AU022554 (e-PCR)
- UniSTS:208658

AW529537 (e-PCR)
- UniSTS:261143

ODZ2_3320 (e-PCR)
- UniSTS:462379

D3Bwg1534e (e-PCR), detects polymorphism
- UniSTS:142384

09.MHAa77a9.seq (e-PCR)
- UniSTS:122959

D11Mit108 (e-PCR), detects polymorphism
- UniSTS:126296

D11Mit51 (e-PCR), detects polymorphism
- UniSTS:126598

AB025411 (e-PCR)
- UniSTS:163495

D5S2458 (e-PCR)
- UniSTS:76484

D11Mit232 (e-PCR), detects polymorphism
- UniSTS:126433

D11Mit233 (e-PCR), detects polymorphism
- UniSTS:126435

Odz2 (e-PCR), detects polymorphism
- UniSTS:507881

Clone Names

mKIAA1127, D3Bwg1534e, 2610040L17Rik, 9330187F13Rik

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables cell adhesion molecule binding	IBA Inferred from Biological aspect of Ancestor more info
enables cell adhesion molecule binding	ISO Inferred from Sequence Orthology more info
enables cell adhesion molecule binding	ISS Inferred from Sequence or Structural Similarity more info
enables identical protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein heterodimerization activity	IBA Inferred from Biological aspect of Ancestor more info
enables protein heterodimerization activity	IDA Inferred from Direct Assay more info	PubMed
enables protein homodimerization activity	IBA Inferred from Biological aspect of Ancestor more info
enables protein homodimerization activity	IDA Inferred from Direct Assay more info	PubMed
enables signaling receptor binding	ISO Inferred from Sequence Orthology more info
enables signaling receptor binding	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
involved_in cell-cell adhesion	ISS Inferred from Sequence or Structural Similarity more info
involved_in heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of transcription by RNA polymerase II	ISS Inferred from Sequence or Structural Similarity more info
involved_in neuron development	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of filopodium assembly	ISS Inferred from Sequence or Structural Similarity more info
involved_in retrograde trans-synaptic signaling by trans-synaptic protein complex	ISO Inferred from Sequence Orthology more info
involved_in signal transduction	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in Golgi apparatus	ISS Inferred from Sequence or Structural Similarity more info
located_in PML body	ISS Inferred from Sequence or Structural Similarity more info
located_in cell junction	ISS Inferred from Sequence or Structural Similarity more info
located_in cell-cell junction	ISO Inferred from Sequence Orthology more info
located_in cell-cell junction	ISS Inferred from Sequence or Structural Similarity more info
located_in dendrite	ISS Inferred from Sequence or Structural Similarity more info
located_in dendritic spine	ISO Inferred from Sequence Orthology more info
located_in dendritic spine	ISS Inferred from Sequence or Structural Similarity more info
located_in endoplasmic reticulum	ISS Inferred from Sequence or Structural Similarity more info
is_active_in extrinsic component of postsynaptic membrane	ISO Inferred from Sequence Orthology more info
located_in filopodium	ISS Inferred from Sequence or Structural Similarity more info
is_active_in glutamatergic synapse	ISO Inferred from Sequence Orthology more info
located_in growth cone	ISS Inferred from Sequence or Structural Similarity more info
is_active_in neuron projection	IBA Inferred from Biological aspect of Ancestor more info
located_in neuron projection	ISO Inferred from Sequence Orthology more info
located_in neuron projection	ISS Inferred from Sequence or Structural Similarity more info
located_in nucleus	ISS Inferred from Sequence or Structural Similarity more info
located_in plasma membrane	ISO Inferred from Sequence Orthology more info
located_in plasma membrane	ISS Inferred from Sequence or Structural Similarity more info	PubMed
located_in postsynaptic membrane	ISO Inferred from Sequence Orthology more info
located_in postsynaptic membrane	ISS Inferred from Sequence or Structural Similarity more info
located_in synapse	ISO Inferred from Sequence Orthology more info
located_in synapse	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: teneurin-2

Names: odd Oz/ten-m homolog 2; protein Odd Oz/ten-m homolog 2; tenascin-M2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001290702.1 → NP_001277631.1 teneurin-2 isoform 2

See identical proteins and their annotated locations for NP_001277631.1

Status: VALIDATED

Description

Transcript Variant: This variant (2) has multiple differences in the coding region but maintains reading frame, compared to variant 1. The encoded isoform (2) is shorter, compared to isoform 1.

Source sequence(s)

AL645912, AL713915, AL713919, AL713956, BX000433, BX539311

UniProtKB/Swiss-Prot

Q5NBW7, Q5NBW8, Q80TJ0, Q9JLC0, Q9QYZ1, Q9WTS5

UniProtKB/TrEMBL

B9EJ72

Conserved Domains (8) summary

COG3209
Location:1648 → 2441

RhsA; Uncharacterized conserved protein RhaS, contains 28 RHS repeats [General function prediction only]

cd05819
Location:1199 → 1238

NHL; NHL repeat [structural motif]

TIGR03696
Location:2350 → 2427

Rhs_assc_core; RHS repeat-associated core domain

pfam07974
Location:539 → 561

EGF_2; EGF-like domain

cl18310
Location:1199 → 1529

NHL; NHL repeat unit of beta-propeller proteins

pfam01500
Location:626 → 744

Keratin_B2; Keratin, high sulfur B2 protein

pfam06484
Location:10 → 374

Ten_N; Teneurin Intracellular Region

pfam15636
Location:2649 → 2726

Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
NM_011856.4 → NP_035986.3 teneurin-2 isoform 1

Status: VALIDATED

Description

Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).

Source sequence(s)

AL645912, AL713915, AL713919, AL713956, BX000433, BX539311

Consensus CDS

CCDS24546.1

UniProtKB/Swiss-Prot

Q5NBW7, Q5NBW8, Q80TJ0, Q9JLC0, Q9QYZ1, Q9WTS5

UniProtKB/TrEMBL

A0A0A0MQB7

Related

ENSMUSP00000129951.2, ENSMUST00000163524.8

Conserved Domains (10) summary

COG3209
Location:1679 → 2472

RhsA; Uncharacterized conserved protein RhaS, contains 28 RHS repeats [General function prediction only]

cd00054
Location:671 → 700

EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...

cd05819
Location:1230 → 1269

NHL; NHL repeat [structural motif]

TIGR03696
Location:2381 → 2458

Rhs_assc_core; RHS repeat-associated core domain

pfam05593
Location:1672 → 1710

RHS_repeat; RHS Repeat

pfam06484
Location:10 → 374

Ten_N; Teneurin Intracellular Region

pfam07974
Location:580 → 602

EGF_2; EGF-like domain

pfam15636
Location:2682 → 2757

Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin

cl18310
Location:1230 → 1560

NHL; NHL repeat unit of beta-propeller proteins

cl19567
Location:725 → 764

DSL; Delta serrate ligand

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

NC_000077.7 Reference GRCm39 C57BL/6J

Range

35897483..37881486 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_036156687.1 → XP_036012580.1 teneurin-2 isoform X1

UniProtKB/Swiss-Prot

Q5NBW7, Q5NBW8, Q80TJ0, Q9JLC0, Q9QYZ1, Q9WTS5

Conserved Domains (7) summary

COG3209
Location:1689 → 2482

RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]

cd05819
Location:1240 → 1279

NHL; NHL repeat [structural motif]

TIGR03696
Location:2391 → 2468

Rhs_assc_core; RHS repeat-associated core domain

cl18310
Location:1240 → 1570

NHL; NHL repeat unit of beta-propeller proteins

pfam06484
Location:10 → 374

Ten_N; Teneurin Intracellular Region

pfam15636
Location:2690 → 2767

Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin

NF033759
Location:570 → 885

exchanger_TraA; outer membrane exchange protein TraA
XM_006533290.4 → XP_006533353.1 teneurin-2 isoform X1

See identical proteins and their annotated locations for XP_006533353.1

UniProtKB/Swiss-Prot

Q5NBW7, Q5NBW8, Q80TJ0, Q9JLC0, Q9QYZ1, Q9WTS5

Conserved Domains (7) summary

COG3209
Location:1689 → 2482

RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]

cd05819
Location:1240 → 1279

NHL; NHL repeat [structural motif]

TIGR03696
Location:2391 → 2468

Rhs_assc_core; RHS repeat-associated core domain

cl18310
Location:1240 → 1570

NHL; NHL repeat unit of beta-propeller proteins

pfam06484
Location:10 → 374

Ten_N; Teneurin Intracellular Region

pfam15636
Location:2690 → 2767

Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin

NF033759
Location:570 → 885

exchanger_TraA; outer membrane exchange protein TraA
XM_030245994.1 → XP_030101854.1 teneurin-2 isoform X1

UniProtKB/Swiss-Prot

Q5NBW7, Q5NBW8, Q80TJ0, Q9JLC0, Q9QYZ1, Q9WTS5

Conserved Domains (7) summary

COG3209
Location:1689 → 2482

RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]

cd05819
Location:1240 → 1279

NHL; NHL repeat [structural motif]

TIGR03696
Location:2391 → 2468

Rhs_assc_core; RHS repeat-associated core domain

cl18310
Location:1240 → 1570

NHL; NHL repeat unit of beta-propeller proteins

pfam06484
Location:10 → 374

Ten_N; Teneurin Intracellular Region

pfam15636
Location:2690 → 2767

Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin

NF033759
Location:570 → 885

exchanger_TraA; outer membrane exchange protein TraA
XM_036156689.1 → XP_036012582.1 teneurin-2 isoform X10

UniProtKB/Swiss-Prot

Q5NBW7, Q5NBW8, Q80TJ0, Q9JLC0, Q9QYZ1, Q9WTS5

Conserved Domains (7) summary

COG3209
Location:1578 → 2371

RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]

cd05819
Location:1129 → 1168

NHL; NHL repeat [structural motif]

TIGR03696
Location:2280 → 2357

Rhs_assc_core; RHS repeat-associated core domain

cl18310
Location:1129 → 1459

NHL; NHL repeat unit of beta-propeller proteins

pfam06484
Location:10 → 304

Ten_N; Teneurin Intracellular Region

pfam15636
Location:2579 → 2656

Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin

NF033759
Location:459 → 774

exchanger_TraA; outer membrane exchange protein TraA
XM_036156690.1 → XP_036012583.1 teneurin-2 isoform X11

UniProtKB/Swiss-Prot

Q5NBW7, Q5NBW8, Q80TJ0, Q9JLC0, Q9QYZ1, Q9WTS5

Conserved Domains (8) summary

COG3209
Location:1548 → 2341

RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]

cd05819
Location:1099 → 1138

NHL; NHL repeat [structural motif]

TIGR03696
Location:2250 → 2327

Rhs_assc_core; RHS repeat-associated core domain

cl18310
Location:1099 → 1429

NHL; NHL repeat unit of beta-propeller proteins

pfam06484
Location:10 → 304

Ten_N; Teneurin Intracellular Region

pfam15636
Location:2549 → 2626

Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin

NF033662
Location:702 → 732

acid_disulf_rpt; acidic double-disulfide repeat

NF033759
Location:500 → 738

exchanger_TraA; outer membrane exchange protein TraA
XM_006533295.4 → XP_006533358.1 teneurin-2 isoform X7

UniProtKB/Swiss-Prot

Q5NBW7, Q5NBW8, Q80TJ0, Q9JLC0, Q9QYZ1, Q9WTS5

Conserved Domains (8) summary

COG3209
Location:1619 → 2412

RhsA; Uncharacterized conserved protein RhaS, contains 28 RHS repeats [General function prediction only]

cd05819
Location:1170 → 1209

NHL; NHL repeat [structural motif]

TIGR03696
Location:2321 → 2398

Rhs_assc_core; RHS repeat-associated core domain

pfam07974
Location:510 → 532

EGF_2; EGF-like domain

cl18310
Location:1170 → 1500

NHL; NHL repeat unit of beta-propeller proteins

pfam01500
Location:597 → 715

Keratin_B2; Keratin, high sulfur B2 protein

pfam06484
Location:10 → 304

Ten_N; Teneurin Intracellular Region

pfam15636
Location:2620 → 2697

Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
XM_011249009.3 → XP_011247311.1 teneurin-2 isoform X6

UniProtKB/Swiss-Prot

Q5NBW7, Q5NBW8, Q80TJ0, Q9JLC0, Q9QYZ1, Q9WTS5

Conserved Domains (8) summary

COG3209
Location:1641 → 2434

RhsA; Uncharacterized conserved protein RhaS, contains 28 RHS repeats [General function prediction only]

cd05819
Location:1199 → 1227

NHL; NHL repeat [structural motif]

TIGR03696
Location:2343 → 2420

Rhs_assc_core; RHS repeat-associated core domain

pfam07974
Location:539 → 561

EGF_2; EGF-like domain

cl18310
Location:1199 → 1522

NHL; NHL repeat unit of beta-propeller proteins

pfam01500
Location:626 → 744

Keratin_B2; Keratin, high sulfur B2 protein

pfam06484
Location:10 → 374

Ten_N; Teneurin Intracellular Region

pfam15636
Location:2642 → 2719

Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
XM_006533287.4 → XP_006533350.1 teneurin-2 isoform X1

See identical proteins and their annotated locations for XP_006533350.1

UniProtKB/Swiss-Prot

Q5NBW7, Q5NBW8, Q80TJ0, Q9JLC0, Q9QYZ1, Q9WTS5

Conserved Domains (7) summary

COG3209
Location:1689 → 2482

RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]

cd05819
Location:1240 → 1279

NHL; NHL repeat [structural motif]

TIGR03696
Location:2391 → 2468

Rhs_assc_core; RHS repeat-associated core domain

cl18310
Location:1240 → 1570

NHL; NHL repeat unit of beta-propeller proteins

pfam06484
Location:10 → 374

Ten_N; Teneurin Intracellular Region

pfam15636
Location:2690 → 2767

Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin

NF033759
Location:570 → 885

exchanger_TraA; outer membrane exchange protein TraA
XM_006533288.4 → XP_006533351.1 teneurin-2 isoform X1

See identical proteins and their annotated locations for XP_006533351.1

UniProtKB/Swiss-Prot

Q5NBW7, Q5NBW8, Q80TJ0, Q9JLC0, Q9QYZ1, Q9WTS5

Conserved Domains (7) summary

COG3209
Location:1689 → 2482

RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]

cd05819
Location:1240 → 1279

NHL; NHL repeat [structural motif]

TIGR03696
Location:2391 → 2468

Rhs_assc_core; RHS repeat-associated core domain

cl18310
Location:1240 → 1570

NHL; NHL repeat unit of beta-propeller proteins

pfam06484
Location:10 → 374

Ten_N; Teneurin Intracellular Region

pfam15636
Location:2690 → 2767

Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin

NF033759
Location:570 → 885

exchanger_TraA; outer membrane exchange protein TraA
XM_030245995.2 → XP_030101855.1 teneurin-2 isoform X9

UniProtKB/Swiss-Prot

Q5NBW7, Q5NBW8, Q80TJ0, Q9JLC0, Q9QYZ1, Q9WTS5

Conserved Domains (10) summary

COG3209
Location:1611 → 2404

RhsA; Uncharacterized conserved protein RhaS, contains 28 RHS repeats [General function prediction only]

cd00054
Location:671 → 700

EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...

cd05819
Location:1169 → 1197

NHL; NHL repeat [structural motif]

TIGR03696
Location:2313 → 2390

Rhs_assc_core; RHS repeat-associated core domain

pfam07974
Location:576 → 602

EGF_2; EGF-like domain

cl18310
Location:1169 → 1492

NHL; NHL repeat unit of beta-propeller proteins

pfam01500
Location:667 → 803

Keratin_B2; Keratin, high sulfur B2 protein

pfam06484
Location:10 → 374

Ten_N; Teneurin Intracellular Region

pfam15636
Location:2612 → 2689

Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin

pfam18372
Location:611 → 628

I-EGF_1; Integrin beta epidermal growth factor like domain 1
XM_006533296.5 → XP_006533359.1 teneurin-2 isoform X8

UniProtKB/Swiss-Prot

Q5NBW7, Q5NBW8, Q80TJ0, Q9JLC0, Q9QYZ1, Q9WTS5

Conserved Domains (10) summary

COG3209
Location:1618 → 2411

RhsA; Uncharacterized conserved protein RhaS, contains 28 RHS repeats [General function prediction only]

cd00054
Location:671 → 700

EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...

cd05819
Location:1169 → 1208

NHL; NHL repeat [structural motif]

TIGR03696
Location:2320 → 2397

Rhs_assc_core; RHS repeat-associated core domain

pfam07974
Location:576 → 602

EGF_2; EGF-like domain

cl18310
Location:1169 → 1499

NHL; NHL repeat unit of beta-propeller proteins

pfam01500
Location:667 → 803

Keratin_B2; Keratin, high sulfur B2 protein

pfam06484
Location:10 → 374

Ten_N; Teneurin Intracellular Region

pfam15636
Location:2619 → 2696

Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin

pfam18372
Location:611 → 628

I-EGF_1; Integrin beta epidermal growth factor like domain 1
XM_006533293.5 → XP_006533356.1 teneurin-2 isoform X4

UniProtKB/Swiss-Prot

Q5NBW7, Q5NBW8, Q80TJ0, Q9JLC0, Q9QYZ1, Q9WTS5

Conserved Domains (9) summary

COG3209
Location:1673 → 2466

RhsA; Uncharacterized conserved protein RhaS, contains 28 RHS repeats [General function prediction only]

cd00054
Location:798 → 831

EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...

cd05819
Location:1231 → 1259

NHL; NHL repeat [structural motif]

TIGR03696
Location:2375 → 2452

Rhs_assc_core; RHS repeat-associated core domain

pfam07974
Location:580 → 602

EGF_2; EGF-like domain

cl18310
Location:1231 → 1554

NHL; NHL repeat unit of beta-propeller proteins

pfam01500
Location:667 → 785

Keratin_B2; Keratin, high sulfur B2 protein

pfam06484
Location:10 → 374

Ten_N; Teneurin Intracellular Region

pfam15636
Location:2674 → 2751

Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
XM_006533292.5 → XP_006533355.1 teneurin-2 isoform X3

UniProtKB/Swiss-Prot

Q5NBW7, Q5NBW8, Q80TJ0, Q9JLC0, Q9QYZ1, Q9WTS5

UniProtKB/TrEMBL

A0A0A0MQ92

Related

ENSMUSP00000052014.6, ENSMUST00000057207.6

Conserved Domains (9) summary

COG3209
Location:1680 → 2473

RhsA; Uncharacterized conserved protein RhaS, contains 28 RHS repeats [General function prediction only]

cd00054
Location:798 → 831

EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...

cd05819
Location:1231 → 1270

NHL; NHL repeat [structural motif]

TIGR03696
Location:2382 → 2459

Rhs_assc_core; RHS repeat-associated core domain

pfam07974
Location:580 → 602

EGF_2; EGF-like domain

cl18310
Location:1231 → 1561

NHL; NHL repeat unit of beta-propeller proteins

pfam01500
Location:667 → 785

Keratin_B2; Keratin, high sulfur B2 protein

pfam06484
Location:10 → 374

Ten_N; Teneurin Intracellular Region

pfam15636
Location:2681 → 2758

Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
XM_006533291.5 → XP_006533354.1 teneurin-2 isoform X2

UniProtKB/Swiss-Prot

Q5NBW7, Q5NBW8, Q80TJ0, Q9JLC0, Q9QYZ1, Q9WTS5

Conserved Domains (8) summary

COG3209
Location:1682 → 2475

RhsA; Uncharacterized conserved protein RhaS, contains 28 RHS repeats [General function prediction only]

cd05819
Location:1240 → 1268

NHL; NHL repeat [structural motif]

TIGR03696
Location:2384 → 2461

Rhs_assc_core; RHS repeat-associated core domain

pfam07974
Location:580 → 602

EGF_2; EGF-like domain

cl18310
Location:1240 → 1563

NHL; NHL repeat unit of beta-propeller proteins

pfam01500
Location:667 → 785

Keratin_B2; Keratin, high sulfur B2 protein

pfam06484
Location:10 → 374

Ten_N; Teneurin Intracellular Region

pfam15636
Location:2683 → 2760

Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
XM_006533289.2 → XP_006533352.1 teneurin-2 isoform X1

See identical proteins and their annotated locations for XP_006533352.1

UniProtKB/Swiss-Prot

Q5NBW7, Q5NBW8, Q80TJ0, Q9JLC0, Q9QYZ1, Q9WTS5

Conserved Domains (7) summary

COG3209
Location:1689 → 2482

RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]

cd05819
Location:1240 → 1279

NHL; NHL repeat [structural motif]

TIGR03696
Location:2391 → 2468

Rhs_assc_core; RHS repeat-associated core domain

cl18310
Location:1240 → 1570

NHL; NHL repeat unit of beta-propeller proteins

pfam06484
Location:10 → 374

Ten_N; Teneurin Intracellular Region

pfam15636
Location:2690 → 2767

Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin

NF033759
Location:570 → 885

exchanger_TraA; outer membrane exchange protein TraA
XM_036156688.1 → XP_036012581.1 teneurin-2 isoform X1

UniProtKB/Swiss-Prot

Q5NBW7, Q5NBW8, Q80TJ0, Q9JLC0, Q9QYZ1, Q9WTS5

Conserved Domains (7) summary

COG3209
Location:1689 → 2482

RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]

cd05819
Location:1240 → 1279

NHL; NHL repeat [structural motif]

TIGR03696
Location:2391 → 2468

Rhs_assc_core; RHS repeat-associated core domain

cl18310
Location:1240 → 1570

NHL; NHL repeat unit of beta-propeller proteins

pfam06484
Location:10 → 374

Ten_N; Teneurin Intracellular Region

pfam15636
Location:2690 → 2767

Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin

NF033759
Location:570 → 885

exchanger_TraA; outer membrane exchange protein TraA
XM_036156696.1 → XP_036012589.1 teneurin-2 isoform X21

UniProtKB/Swiss-Prot

Q5NBW7, Q5NBW8, Q80TJ0, Q9JLC0, Q9QYZ1, Q9WTS5

Conserved Domains (7) summary

COG3209
Location:1426 → 2219

RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]

cd05819
Location:977 → 1016

NHL; NHL repeat [structural motif]

TIGR03696
Location:2128 → 2205

Rhs_assc_core; RHS repeat-associated core domain

cl18310
Location:977 → 1307

NHL; NHL repeat unit of beta-propeller proteins

pfam06484
Location:14 → 152

Ten_N; Teneurin Intracellular Region

pfam15636
Location:2427 → 2504

Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin

NF033759
Location:307 → 622

exchanger_TraA; outer membrane exchange protein TraA
XM_036156698.1 → XP_036012591.1 teneurin-2 isoform X24

UniProtKB/Swiss-Prot

Q5NBW7, Q5NBW8, Q80TJ0, Q9JLC0, Q9QYZ1, Q9WTS5

Conserved Domains (8) summary

COG3209
Location:1396 → 2189

RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]

cd05819
Location:947 → 986

NHL; NHL repeat [structural motif]

TIGR03696
Location:2098 → 2175

Rhs_assc_core; RHS repeat-associated core domain

cl18310
Location:947 → 1277

NHL; NHL repeat unit of beta-propeller proteins

pfam06484
Location:14 → 152

Ten_N; Teneurin Intracellular Region

pfam15636
Location:2397 → 2474

Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin

NF033662
Location:550 → 580

acid_disulf_rpt; acidic double-disulfide repeat

NF033759
Location:348 → 586

exchanger_TraA; outer membrane exchange protein TraA
XM_006533301.5 → XP_006533364.1 teneurin-2 isoform X19

UniProtKB/Swiss-Prot

Q5NBW7, Q5NBW8, Q80TJ0, Q9JLC0, Q9QYZ1, Q9WTS5

Conserved Domains (8) summary

COG3209
Location:1467 → 2260

RhsA; Uncharacterized conserved protein RhaS, contains 28 RHS repeats [General function prediction only]

cd05819
Location:1018 → 1057

NHL; NHL repeat [structural motif]

TIGR03696
Location:2169 → 2246

Rhs_assc_core; RHS repeat-associated core domain

pfam07974
Location:358 → 380

EGF_2; EGF-like domain

cl18310
Location:1018 → 1348

NHL; NHL repeat unit of beta-propeller proteins

pfam01500
Location:445 → 563

Keratin_B2; Keratin, high sulfur B2 protein

pfam06484
Location:10 → 152

Ten_N; Teneurin Intracellular Region

pfam15636
Location:2468 → 2545

Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
XM_036156697.1 → XP_036012590.1 teneurin-2 isoform X22

UniProtKB/Swiss-Prot

Q5NBW7, Q5NBW8, Q80TJ0, Q9JLC0, Q9QYZ1, Q9WTS5

Conserved Domains (8) summary

COG3209
Location:1425 → 2218

RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]

cd05819
Location:976 → 1015

NHL; NHL repeat [structural motif]

TIGR03696
Location:2127 → 2204

Rhs_assc_core; RHS repeat-associated core domain

cl18310
Location:976 → 1306

NHL; NHL repeat unit of beta-propeller proteins

pfam06484
Location:10 → 222

Ten_N; Teneurin Intracellular Region

pfam15636
Location:2426 → 2503

Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin

NF033662
Location:579 → 609

acid_disulf_rpt; acidic double-disulfide repeat

NF033759
Location:377 → 615

exchanger_TraA; outer membrane exchange protein TraA
XM_036156694.1 → XP_036012587.1 teneurin-2 isoform X18

UniProtKB/Swiss-Prot

Q5NBW7, Q5NBW8, Q80TJ0, Q9JLC0, Q9QYZ1, Q9WTS5

Conserved Domains (7) summary

COG3209
Location:1487 → 2280

RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]

cd05819
Location:1038 → 1077

NHL; NHL repeat [structural motif]

TIGR03696
Location:2189 → 2266

Rhs_assc_core; RHS repeat-associated core domain

cl18310
Location:1038 → 1368

NHL; NHL repeat unit of beta-propeller proteins

pfam06484
Location:10 → 222

Ten_N; Teneurin Intracellular Region

pfam15636
Location:2488 → 2565

Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin

NF033759
Location:377 → 683

exchanger_TraA; outer membrane exchange protein TraA
XM_036156693.1 → XP_036012586.1 teneurin-2 isoform X16

UniProtKB/Swiss-Prot

Q5NBW7, Q5NBW8, Q80TJ0, Q9JLC0, Q9QYZ1, Q9WTS5

Conserved Domains (7) summary

COG3209
Location:1496 → 2289

RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]

cd05819
Location:1047 → 1086

NHL; NHL repeat [structural motif]

TIGR03696
Location:2198 → 2275

Rhs_assc_core; RHS repeat-associated core domain

cl18310
Location:1047 → 1377

NHL; NHL repeat unit of beta-propeller proteins

pfam06484
Location:10 → 222

Ten_N; Teneurin Intracellular Region

pfam15636
Location:2497 → 2574

Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin

NF033759
Location:377 → 692

exchanger_TraA; outer membrane exchange protein TraA
XM_036156695.1 → XP_036012588.1 teneurin-2 isoform X20

UniProtKB/Swiss-Prot

Q5NBW7, Q5NBW8, Q80TJ0, Q9JLC0, Q9QYZ1, Q9WTS5

Conserved Domains (8) summary

COG3209
Location:1466 → 2259

RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]

cd05819
Location:1017 → 1056

NHL; NHL repeat [structural motif]

TIGR03696
Location:2168 → 2245

Rhs_assc_core; RHS repeat-associated core domain

cl18310
Location:1017 → 1347

NHL; NHL repeat unit of beta-propeller proteins

pfam06484
Location:10 → 222

Ten_N; Teneurin Intracellular Region

pfam15636
Location:2467 → 2544

Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin

NF033662
Location:620 → 650

acid_disulf_rpt; acidic double-disulfide repeat

NF033759
Location:418 → 656

exchanger_TraA; outer membrane exchange protein TraA
XM_036156692.1 → XP_036012585.1 teneurin-2 isoform X14

UniProtKB/Swiss-Prot

Q5NBW7, Q5NBW8, Q80TJ0, Q9JLC0, Q9QYZ1, Q9WTS5

Conserved Domains (7) summary

COG3209
Location:1528 → 2321

RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]

cd05819
Location:1079 → 1118

NHL; NHL repeat [structural motif]

TIGR03696
Location:2230 → 2307

Rhs_assc_core; RHS repeat-associated core domain

cl18310
Location:1079 → 1409

NHL; NHL repeat unit of beta-propeller proteins

pfam06484
Location:10 → 222

Ten_N; Teneurin Intracellular Region

pfam15636
Location:2529 → 2606

Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin

NF033759
Location:418 → 724

exchanger_TraA; outer membrane exchange protein TraA
XM_036156691.1 → XP_036012584.1 teneurin-2 isoform X13

UniProtKB/Swiss-Prot

Q5NBW7, Q5NBW8, Q80TJ0, Q9JLC0, Q9QYZ1, Q9WTS5

Conserved Domains (7) summary

COG3209
Location:1530 → 2323

RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]

cd05819
Location:1088 → 1116

NHL; NHL repeat [structural motif]

TIGR03696
Location:2232 → 2309

Rhs_assc_core; RHS repeat-associated core domain

cl18310
Location:1088 → 1411

NHL; NHL repeat unit of beta-propeller proteins

pfam06484
Location:10 → 222

Ten_N; Teneurin Intracellular Region

pfam15636
Location:2531 → 2608

Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin

NF033759
Location:418 → 733

exchanger_TraA; outer membrane exchange protein TraA
XM_006533297.5 → XP_006533360.1 teneurin-2 isoform X12

UniProtKB/Swiss-Prot

Q5NBW7, Q5NBW8, Q80TJ0, Q9JLC0, Q9QYZ1, Q9WTS5

Conserved Domains (8) summary

COG3209
Location:1537 → 2330

RhsA; Uncharacterized conserved protein RhaS, contains 28 RHS repeats [General function prediction only]

cd05819
Location:1088 → 1127

NHL; NHL repeat [structural motif]

TIGR03696
Location:2239 → 2316

Rhs_assc_core; RHS repeat-associated core domain

pfam07974
Location:428 → 450

EGF_2; EGF-like domain

cl18310
Location:1088 → 1418

NHL; NHL repeat unit of beta-propeller proteins

pfam01500
Location:515 → 633

Keratin_B2; Keratin, high sulfur B2 protein

pfam06484
Location:10 → 222

Ten_N; Teneurin Intracellular Region

pfam15636
Location:2538 → 2615

Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
XM_030245996.2 → XP_030101856.1 teneurin-2 isoform X23

UniProtKB/Swiss-Prot

Q5NBW7, Q5NBW8, Q80TJ0, Q9JLC0, Q9QYZ1, Q9WTS5

Conserved Domains (10) summary

COG3209
Location:1421 → 2214

RhsA; Uncharacterized conserved protein RhaS, contains 28 RHS repeats [General function prediction only]

cd00054
Location:474 → 503

EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...

cd05819
Location:972 → 1011

NHL; NHL repeat [structural motif]

TIGR03696
Location:2123 → 2200

Rhs_assc_core; RHS repeat-associated core domain

pfam07974
Location:379 → 405

EGF_2; EGF-like domain

cl18310
Location:972 → 1302

NHL; NHL repeat unit of beta-propeller proteins

pfam01500
Location:470 → 606

Keratin_B2; Keratin, high sulfur B2 protein

pfam06484
Location:1 → 177

Ten_N; Teneurin Intracellular Region

pfam15636
Location:2422 → 2499

Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin

pfam18372
Location:414 → 431

I-EGF_1; Integrin beta epidermal growth factor like domain 1
XM_017314549.2 → XP_017170038.1 teneurin-2 isoform X17

UniProtKB/Swiss-Prot

Q5NBW7, Q5NBW8, Q80TJ0, Q9JLC0, Q9QYZ1, Q9WTS5

Conserved Domains (8) summary

COG3209
Location:1492 → 2285

RhsA; Uncharacterized conserved protein RhaS, contains 28 RHS repeats [General function prediction only]

cd05819
Location:1043 → 1082

NHL; NHL repeat [structural motif]

TIGR03696
Location:2194 → 2271

Rhs_assc_core; RHS repeat-associated core domain

pfam07974
Location:383 → 405

EGF_2; EGF-like domain

cl18310
Location:1043 → 1373

NHL; NHL repeat unit of beta-propeller proteins

pfam01500
Location:470 → 588

Keratin_B2; Keratin, high sulfur B2 protein

pfam06484
Location:1 → 177

Ten_N; Teneurin Intracellular Region

pfam15636
Location:2493 → 2570

Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
XM_017314548.2 → XP_017170037.1 teneurin-2 isoform X17

UniProtKB/Swiss-Prot

Q5NBW7, Q5NBW8, Q80TJ0, Q9JLC0, Q9QYZ1, Q9WTS5

Conserved Domains (8) summary

COG3209
Location:1492 → 2285

RhsA; Uncharacterized conserved protein RhaS, contains 28 RHS repeats [General function prediction only]

cd05819
Location:1043 → 1082

NHL; NHL repeat [structural motif]

TIGR03696
Location:2194 → 2271

Rhs_assc_core; RHS repeat-associated core domain

pfam07974
Location:383 → 405

EGF_2; EGF-like domain

cl18310
Location:1043 → 1373

NHL; NHL repeat unit of beta-propeller proteins

pfam01500
Location:470 → 588

Keratin_B2; Keratin, high sulfur B2 protein

pfam06484
Location:1 → 177

Ten_N; Teneurin Intracellular Region

pfam15636
Location:2493 → 2570

Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
XM_006533298.3 → XP_006533361.1 teneurin-2 isoform X15

See identical proteins and their annotated locations for XP_006533361.1

UniProtKB/Swiss-Prot

Q5NBW7, Q5NBW8, Q80TJ0, Q9JLC0, Q9QYZ1, Q9WTS5

Conserved Domains (8) summary

COG3209
Location:1527 → 2320

RhsA; Uncharacterized conserved protein RhaS, contains 28 RHS repeats [General function prediction only]

cd05819
Location:1078 → 1117

NHL; NHL repeat [structural motif]

TIGR03696
Location:2229 → 2306

Rhs_assc_core; RHS repeat-associated core domain

pfam07974
Location:418 → 440

EGF_2; EGF-like domain

cl18310
Location:1078 → 1408

NHL; NHL repeat unit of beta-propeller proteins

pfam01500
Location:505 → 623

Keratin_B2; Keratin, high sulfur B2 protein

pfam06484
Location:4 → 212

Ten_N; Teneurin Intracellular Region

pfam15636
Location:2528 → 2605

Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
XM_006533294.5 → XP_006533357.1 teneurin-2 isoform X5

See identical proteins and their annotated locations for XP_006533357.1

UniProtKB/Swiss-Prot

Q5NBW7, Q5NBW8, Q80TJ0, Q9JLC0, Q9QYZ1, Q9WTS5

UniProtKB/TrEMBL

B9EJ72

Conserved Domains (8) summary

COG3209
Location:1648 → 2441

RhsA; Uncharacterized conserved protein RhaS, contains 28 RHS repeats [General function prediction only]

cd05819
Location:1199 → 1238

NHL; NHL repeat [structural motif]

TIGR03696
Location:2350 → 2427

Rhs_assc_core; RHS repeat-associated core domain

pfam07974
Location:539 → 561

EGF_2; EGF-like domain

cl18310
Location:1199 → 1529

NHL; NHL repeat unit of beta-propeller proteins

pfam01500
Location:626 → 744

Keratin_B2; Keratin, high sulfur B2 protein

pfam06484
Location:10 → 374

Ten_N; Teneurin Intracellular Region

pfam15636
Location:2649 → 2726

Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin