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    DIP-eta Dpr-interacting protein eta [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33793, updated on 9-Dec-2024

    Summary

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    Official Symbol
    DIP-etaprovided by FlyBase
    Official Full Name
    Dpr-interacting protein etaprovided by FlyBase
    Primary source
    FLYBASE:FBgn0031725
    Locus tag
    Dmel_CG14010
    See related
    AllianceGenome:FB:FBgn0031725
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    14010; CG14010; CT33567; DIPeta; Dmel\CG14010
    Summary
    Involved in synapse organization. Predicted to be located in plasma membrane. Predicted to be active in neuron projection. Is expressed in optic lobe intrinsic columnar neurons. Human ortholog(s) of this gene implicated in ovarian cancer. Orthologous to several human genes including IGLON5 (IgLON family member 5); NTM (neurotrimin); and OPCML (opioid binding protein/cell adhesion molecule like). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See DIP-eta in Genome Data Viewer
    Location:
    25F1-25F1; 2-17 cM
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (5601723..5617946, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (5601723..5617946, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44795 Neighboring gene long non-coding RNA:CR44796 Neighboring gene Cytochrome P450 6a16

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic Architecture of Natural Variation Underlying Adult Foraging Behavior That Is Essential for Survival of Drosophila melanogaster. Lee YCG, et al. Genome Biol Evol, 2017 May 1. PMID 28472322, Free PMC Article
    2. Molecular basis of synaptic specificity by immunoglobulin superfamily receptors in Drosophila. Cheng S, et al. Elife, 2019 Jan 28. PMID 30688651, Free PMC Article
    3. Classifying Protein-Protein Binding Affinity with Free-Energy Calculations and Machine Learning Approaches. Goulard Coderc de Lacam E, et al. J Chem Inf Model, 2024 Feb 12. PMID 38272021
    4. Drosophila TET acts with PRC1 to activate gene expression independently of its catalytic activity. Gilbert G, et al. Sci Adv, 2024 May 3. PMID 38701218, Free PMC Article
    5. Combinations of DIPs and Dprs control organization of olfactory receptor neuron terminals in Drosophila. Barish S, et al. PLoS Genet, 2018 Aug. PMID 30102700, Free PMC Article

    See all (42) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    mobile_element

    • Loc: c5608668-5608581 mobile_element_type = transposon:INE-1{}5109

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in synapse organization IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in neuron projection IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Dpr-interacting protein eta
    Names
    CG14010-PB
    CG14010-PD
    DIP-eta-PB
    DIP-eta-PD

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      5601723..5617946 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_135102.3 → NP_608946.3  Dpr-interacting protein eta, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_608946.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9MRF8, Q9VMN9
      Conserved Domains (3) summary
      cd00096
      Location:258 → 333
      Ig; Immunoglobulin domain
      smart00410
      Location:153 → 237
      IG_like; Immunoglobulin like
      cl11960
      Location:161 → 224
      Ig; Immunoglobulin domain

    2. NM_001201772.2 → NP_001188701.2  Dpr-interacting protein eta, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001188701.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9MRF8, Q9VMN9
      Conserved Domains (3) summary
      cd00096
      Location:258 → 333
      Ig; Immunoglobulin domain
      smart00410
      Location:153 → 237
      IG_like; Immunoglobulin like
      cl11960
      Location:161 → 224
      Ig; Immunoglobulin domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VMN9 Q9VMN9

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