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    Galnt17 polypeptide N-acetylgalactosaminyltransferase 17 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 288611, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Galnt17provided by RGD
    Official Full Name
    polypeptide N-acetylgalactosaminyltransferase 17provided by RGD
    Primary source
    RGD:1563452
    See related
    EnsemblRapid:ENSRNOG00000024435 AllianceGenome:RGD:1563452
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Wbscr17
    Summary
    Predicted to enable carbohydrate binding activity and polypeptide N-acetylgalactosaminyltransferase activity. Predicted to be involved in protein glycosylation. Predicted to be located in Golgi membrane. Orthologous to human GALNT17 (polypeptide N-acetylgalactosaminyltransferase 17). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Muscle (RPKM 64.6), Uterus (RPKM 62.6) and 4 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Galnt17 in Genome Data Viewer
    Location:
    12q12
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 12 NC_086030.1 (30959460..31418150)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 12 NC_051347.1 (25323230..25781897)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 12 NC_005111.4 (28381879..29268457)

    Chromosome 12 - NC_086030.1Genomic Context describing neighboring genes Neighboring gene activator of transcription and developmental regulator AUTS2 Neighboring gene uncharacterized LOC134481283 Neighboring gene uncharacterized LOC120095842 Neighboring gene uncharacterized LOC102550645 Neighboring gene calneuron 1 Neighboring gene transfer RNA serine (anticodon AGA) 21

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Cloning and expression of a brain-specific putative UDP-GalNAc: polypeptide N-acetylgalactosaminyltransferase gene. Nakamura N, et al. Biol Pharm Bull, 2005 Mar. PMID 15744064
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables carbohydrate binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables polypeptide N-acetylgalactosaminyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables polypeptide N-acetylgalactosaminyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein O-linked glycosylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein glycosylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    polypeptide N-acetylgalactosaminyltransferase 17
    Names
    Williams-Beuren syndrome chromosome region 17 homolog
    pt-GalNAc-T
    putative polypeptide N-acetylgalactosaminyltransferase-like protein 3
    NP_001020283.1
    XP_038945146.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001025112.2 → NP_001020283.1  polypeptide N-acetylgalactosaminyltransferase 17 precursor

      See identical proteins and their annotated locations for NP_001020283.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000012
      UniProtKB/TrEMBL
      A0A096MIV6, A0A9K3Y768, Q5CD99
      Related
      ENSRNOP00000067894.2, ENSRNOT00000076101.3
      Conserved Domains (4) summary
      cd02510
      Location:155 → 454
      pp-GalNAc-T; pp-GalNAc-T initiates the formation of mucin-type O-linked glycans
      COG1216
      Location:156 → 459
      GT2; Glycosyltransferase, GT2 family [Carbohydrate transport and metabolism]
      cd00161
      Location:467 → 593
      RICIN; Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific ...
      pfam00652
      Location:465 → 591
      Ricin_B_lectin; Ricin-type beta-trefoil lectin domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086030.1 Reference GRCr8

      Range
      30959460..31418150
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039089218.2 → XP_038945146.1  polypeptide N-acetylgalactosaminyltransferase 17 isoform X1

      Related
      ENSRNOP00000106915.1, ENSRNOT00000124260.1
      Conserved Domains (2) summary
      cd02510
      Location:96 → 395
      pp-GalNAc-T; pp-GalNAc-T initiates the formation of mucin-type O-linked glycans
      cd00161
      Location:408 → 534
      RICIN; Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific ...
    Nucleotide Protein Strain
    Heading Accession and Version

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