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    cysG multifunctional uroporphyrin-III C-methyltransferase/precorrin-2 oxidase/ferrochelatase [ Mycobacterium tuberculosis H37Rv ]

    Gene ID: 887481, updated on 6-Oct-2023

    Summary

    Gene symbol
    cysG
    Gene description
    multifunctional uroporphyrin-III C-methyltransferase/precorrin-2 oxidase/ferrochelatase
    Locus tag
    Rv2847c
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
    Lineage
    Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
    Also known as
    cysG2
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    Genomic context

    Sequence:
    NC_000962.3 (3154654..3155871, complement)

    NC_000962.3Genomic Context describing neighboring genes Neighboring gene proline--tRNA ligase Neighboring gene MFS-type transporter EfpA Neighboring gene cobyrinic acid A,C-diamide synthase Neighboring gene cob(I)alamin adenosyltransferase Neighboring gene magnesium chelatase Neighboring gene GCN5-like N-acetyltransferase

    Pathways from PubChem

    General protein information

    Preferred Names
    multifunctional uroporphyrin-III C-methyltransferase/precorrin-2 oxidase/ferrochelatase
    NP_215025.2
    • Possible cysG urogen III methylase) (SUMT) (uroporphyrinogen III methylase) (UROM)/precorrin-2 oxidase/ferrochelatase

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000962.3 Reference assembly

      Range
      3154654..3155871 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_215025.2 multifunctional uroporphyrin-III C-methyltransferase/precorrin-2 oxidase/ferrochelatase [Mycobacterium tuberculosis H37Rv]

      See identical proteins and their annotated locations for NP_215025.2

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A654U1S1
      Conserved Domains (2) summary
      COG1648
      Location:24152
      CysG2; Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain) [Coenzyme transport and metabolism]
      cd11642
      Location:165394
      SUMT; Uroporphyrin-III C-methyltransferase (also known as S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT)