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    GRK7 G protein-coupled receptor kinase 7 [ Sus scrofa (pig) ]

    Gene ID: 397114, updated on 17-Aug-2024

    Summary

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    Official Symbol
    GRK7provided by VGNC
    Official Full Name
    G protein-coupled receptor kinase 7provided by VGNC
    Primary source
    VGNC:VGNC:88699
    See related
    Ensembl:ENSSSCG00000011675
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Sus scrofa
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
    Also known as
    GPRK7
    Expression
    Biased expression in ovary (RPKM 4.7) and heart (RPKM 0.2) See more
    Orthologs
    human all
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    Genomic context

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    See GRK7 in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    106 current Sscrofa11.1 (GCF_000003025.6) 13 NC_010455.5 (82577604..82630689)
    105 previous assembly Sscrofa10.2 (GCF_000003025.5) 13 NC_010455.4 (90386967..90460565)

    Chromosome 13 - NC_010455.5Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102160777 Neighboring gene leucine rich repeat containing 78 Neighboring gene ring finger protein 7 Neighboring gene uncharacterized LOC110256308 Neighboring gene ATPase Na+/K+ transporting subunit beta 3 Neighboring gene 60S ribosomal protein L21 pseudogene Neighboring gene transcription factor Dp-2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Transcriptome data used for gene annotation
    • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
    • BioProject: PRJNA311523
    • Publication: PMID 27646534
    • Analysis date: Thu Dec 14 17:10:49 2017

    Bibliography

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    Related articles in PubMed

    1. Species-specific differences in expression of G-protein-coupled receptor kinase (GRK) 7 and GRK1 in mammalian cone photoreceptor cells: implications for cone cell phototransduction. Weiss ER, et al. J Neurosci, 2001 Dec 1. PMID 11717351, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables rhodopsin kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    rhodopsin kinase GRK7; rhodopsin kinase
    Names
    g protein-coupled receptor kinase GRK7
    NP_999212.1
    XP_020924190.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_214047.1 → NP_999212.1  rhodopsin kinase GRK7

      See identical proteins and their annotated locations for NP_999212.1

      Status: PROVISIONAL

      Source sequence(s)
      AF282270
      UniProtKB/Swiss-Prot
      Q8WP15
      UniProtKB/TrEMBL
      A0A8D0VQ24
      Related
      ENSSSCP00000012443.1, ENSSSCT00000012780.2
      Conserved Domains (2) summary
      cd05607
      Location:188 → 474
      STKc_GRK7; Catalytic domain of the Protein Serine/Threonine Kinase, G protein-coupled Receptor Kinase 7
      cl02565
      Location:40 → 181
      RGS; Regulator of G protein signaling (RGS) domain superfamily

    RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Sscrofa11.1 Primary Assembly

    Genomic

    1. NC_010455.5 Reference Sscrofa11.1 Primary Assembly

      Range
      82577604..82630689
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021068531.1 → XP_020924190.1  rhodopsin kinase isoform X1

      UniProtKB/TrEMBL
      A0A8D0VQ24
      Conserved Domains (2) summary
      cl02565
      Location:40 → 181
      RGS; Regulator of G protein signaling (RGS) domain superfamily
      cl21453
      Location:188 → 459
      PKc_like; Protein Kinases, catalytic domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8WP15.1 GenPept UniProtKB/Swiss-Prot:Q8WP15

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