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    GMH1 Gmh1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 853901, updated on 9-Dec-2024

    Summary

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    Official Symbol
    GMH1
    Official Full Name
    Gmh1p
    Primary source
    SGD:S000001738
    Locus tag
    YKR030W
    See related
    AllianceGenome:SGD:S000001738; FungiDB:YKR030W; VEuPathDB:YKR030W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    MSG1
    Summary
    Involved in vesicle-mediated transport. Located in Golgi membrane. Orthologous to human UNC50 (unc-50 inner nuclear membrane RNA binding protein). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See GMH1 in Genome Data Viewer
    Location:
    chromosome: XI
    Exon count:
    1
    Sequence:
    Chromosome: XI; NC_001143.9 (500282..501103)

    Chromosome XI - NC_001143.9Genomic Context describing neighboring genes Neighboring gene Sap190p Neighboring gene histone-binding protein SET3 Neighboring gene phospholipase D Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001143.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A novel Golgi membrane protein is a partner of the ARF exchange factors Gea1p and Gea2p. Chantalat S, et al. Mol Biol Cell, 2003 Jun. PMID 12808035, Free PMC Article
    2. The product of Saccharomyces cerevisiae WHIP/MGS1, a gene related to replication factor C genes, interacts functionally with DNA polymerase delta. Branzei D, et al. Mol Genet Genomics, 2002 Nov. PMID 12436259
    3. Predicting protein functions from redundancies in large-scale protein interaction networks. Samanta MP, et al. Proc Natl Acad Sci U S A, 2003 Oct 28. PMID 14566057, Free PMC Article
    4. Systems analysis of the genetic interaction network of yeast molecular chaperones. Rizzolo K, et al. Mol Omics, 2018 Apr 16. PMID 29659649
    5. A combined experimental and computational strategy to define protein interaction networks for peptide recognition modules. Tong AH, et al. Science, 2002 Jan 11. PMID 11743162

    See all (25) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in vesicle-mediated transport IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in Golgi membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in Golgi membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Gmh1p
    NP_012955.1
    • Golgi membrane hypothetical protein; interacts with Gea1p and Gea2p; required for localization of Gea2p; computational analysis suggests a possible role in either cell wall synthesis or protein-vacuolar targeting; conserved from yeast to human

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001143.9 Reference assembly

      Range
      500282..501103
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179820.1 → NP_012955.1  TPA: Gmh1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012955.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VX95, P36125
      UniProtKB/TrEMBL
      A6ZZZ4, B3LRB3, C7GNN0, C8ZCJ4, G2WI62, N1P0W6
      Conserved Domains (1) summary
      pfam05216
      Location:41 → 273
      UNC-50; UNC-50 family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P36125.1

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