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    SKG3 Skg3p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 850884, updated on 9-Dec-2024

    Summary

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    Official Symbol
    SKG3
    Official Full Name
    Skg3p
    Primary source
    SGD:S000004177
    Locus tag
    YLR187W
    See related
    AllianceGenome:SGD:S000004177; FungiDB:YLR187W; VEuPathDB:YLR187W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable protein kinase activity. Predicted to be involved in signal transduction. Located in cellular bud neck; cellular bud tip; and cytoplasm. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See SKG3 in Genome Data Viewer
    Location:
    chromosome: XII
    Exon count:
    1
    Sequence:
    Chromosome: XII; NC_001144.5 (524865..527945)

    Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene ribosomal 60S subunit protein L37A Neighboring gene 18S rRNA pseudouridine methyltransferase Neighboring gene ATP-binding cassette permease MDL1 Neighboring gene sterol 3-beta-glucosyltransferase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001144.5

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A screen for genes of heme uptake identifies the FLC family required for import of FAD into the endoplasmic reticulum. Protchenko O, et al. J Biol Chem, 2006 Jul 28. PMID 16717099
    2. SKG1, a suppressor gene of synthetic lethality of kex2Deltagas1Delta mutations, encodes a novel membrane protein that affects cell wall composition. Tomishige N, et al. Yeast, 2005 Jan 30. PMID 15645486
    3. Single-Cell Based Quantitative Assay of Chromosome Transmission Fidelity. Zhu J, et al. G3 (Bethesda), 2015 Mar 30. PMID 25823586, Free PMC Article
    4. The calcineurin signaling network evolves via conserved kinase-phosphatase modules that transcend substrate identity. Goldman A, et al. Mol Cell, 2014 Aug 7. PMID 24930733, Free PMC Article
    5. Identification and characterization of Prp45p and Prp46p, essential pre-mRNA splicing factors. Albers M, et al. RNA, 2003 Jan. PMID 12554883, Free PMC Article

    See all (34) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    enables protein kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in cellular bud HDA PubMed 
    located_in cellular bud neck HDA PubMed 
    located_in cellular bud neck IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cellular bud tip HDA PubMed 
    located_in cytoplasm HDA PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Skg3p
    NP_013288.1
    • hypothetical protein; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery, cytoplasm, bud, and bud neck; potential Cdc28p substrate; similar to Skg4p; relocalizes from bud neck to cytoplasm upon DNA replication stress; SKG3 has a paralog, CAF120, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001144.5 Reference assembly

      Range
      524865..527945
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182074.1 → NP_013288.1  TPA: Skg3p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013288.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VYJ0, Q06315
      UniProtKB/TrEMBL
      G2WJ19, N1NZS5
      Conserved Domains (1) summary
      pfam00169
      Location:103 → 220
      PH; PH domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q06315.1

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