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    YMD8 Ymd8p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854970, updated on 9-Dec-2024

    Summary

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    Official Symbol
    YMD8
    Official Full Name
    Ymd8p
    Primary source
    SGD:S000004502
    Locus tag
    YML038C
    See related
    AllianceGenome:SGD:S000004502; FungiDB:YML038C; VEuPathDB:YML038C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable antiporter activity and nucleotide-sugar transmembrane transporter activity. Involved in UDP-glucose transmembrane transport. Located in COPI-coated vesicle. Orthologous to human SLC35C2 (solute carrier family 35 member C2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See YMD8 in Genome Data Viewer
    Location:
    chromosome: XIII
    Exon count:
    1
    Sequence:
    Chromosome: XIII; NC_001145.3 (202775..204103, complement)

    Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene tRNA-Pro Neighboring gene gag protein Neighboring gene gag-pol fusion protein Neighboring gene Lft1p Neighboring gene Cgi121p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001145.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The VRG4 gene is required for GDP-mannose transport into the lumen of the Golgi in the yeast, Saccharomyces cerevisiae. Dean N, et al. J Biol Chem, 1997 Dec 12. PMID 9395539
    2. Similarities between UDP-glucose and adenine nucleotide release in yeast: involvement of the secretory pathway. Esther CR Jr, et al. Biochemistry, 2008 Sep 2. PMID 18693752, Free PMC Article
    3. Regulation of stress response signaling by the N-terminal dishevelled/EGL-10/pleckstrin domain of Sst2, a regulator of G protein signaling in Saccharomyces cerevisiae. Burchett SA, et al. J Biol Chem, 2002 Jun 21. PMID 11940600
    4. The phox homology (PX) domain protein interaction network in yeast. Vollert CS, et al. Mol Cell Proteomics, 2004 Nov. PMID 15263065
    5. Genetic interaction network of the Saccharomyces cerevisiae type 1 phosphatase Glc7. Logan MR, et al. BMC Genomics, 2008 Jul 15. PMID 18627629, Free PMC Article

    See all (34) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables antiporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables nucleotide-sugar transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in UDP-glucose transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in UDP-glucose transmembrane transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in nucleotide-sugar transmembrane transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in COPI-coated vesicle HDA PubMed 
    located_in COPI-coated vesicle membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in cis-Golgi network IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasmic vesicle IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in endoplasmic reticulum-Golgi intermediate compartment IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Ymd8p
    NP_013674.1
    • Putative nucleotide sugar transporter; has similarity to Vrg4p

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001145.3 Reference assembly

      Range
      202775..204103 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182396.1 → NP_013674.1  TPA: Ymd8p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013674.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VZD7, Q03697
      UniProtKB/TrEMBL
      A6ZM25, B3LLL5, C7GT67, C8ZEG7
      Conserved Domains (1) summary
      cd21092
      Location:77 → 371
      TPT_S35C2; solute carrier family 35 member C2, member of the triose-phosphate transporter family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q03697.1

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