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    SGO1 Sgo1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854240, updated on 9-Dec-2024

    Summary

    Official Symbol
    SGO1
    Official Full Name
    Sgo1p
    Primary source
    SGD:S000005599
    Locus tag
    YOR073W
    See related
    AllianceGenome:SGD:S000005599; FungiDB:YOR073W; VEuPathDB:YOR073W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    YOR29-24
    Summary
    Involved in several processes, including chromosome organization; meiotic sister chromatid separation; and regulation of chromosome organization. Located in kinetochore. Is active in chromosome, centromeric region. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See SGO1 in Genome Data Viewer
    Location:
    chromosome: XV
    Exon count:
    1
    Sequence:
    Chromosome: XV; NC_001147.6 (464771..466543)

    Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene tRNA-Pro Neighboring gene thymidylate synthase Neighboring gene Ufe1p

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in cell division IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in centromere complex assembly IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in chromosome segregation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in establishment of protein localization IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in establishment of protein localization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in establishment of protein localization to chromosome IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in kinetochore organization IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in kinetochore organization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in maintenance of meiotic sister chromatid cohesion IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in meiotic cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in meiotic chromosome segregation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in meiotic sister chromatid segregation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in meiotic sister chromatid separation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in mitotic cell cycle IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in mitotic cell cycle process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in mitotic sister chromatid segregation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in mitotic sister chromatid segregation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in mitotic spindle assembly checkpoint signaling IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in mitotic spindle assembly checkpoint signaling IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of maintenance of meiotic sister chromatid cohesion IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in positive regulation of maintenance of meiotic sister chromatid cohesion IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in sister chromatid biorientation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in chromosome IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in chromosome, centromeric region IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in chromosome, centromeric region IEA
    Inferred from Electronic Annotation
    more info
     
    located_in condensed chromosome, centromeric region IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in condensed chromosome, centromeric region IEA
    Inferred from Electronic Annotation
    more info
     
    located_in condensed chromosome, centromeric region IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    located_in kinetochore IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in kinetochore IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus HDA PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in spindle pole IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    Sgo1p
    NP_014716.1
    • Component of the spindle checkpoint; involved in sensing lack of tension on mitotic chromosomes; protects centromeric Rec8p at meiosis I; required for accurate chromosomal segregation at meiosis II and for mitotic chromosome stability; recruits condensin to the pericentric region of chromosomes during meiosis; dissociates from pericentromeres when sister kinetochores are under tension

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001147.6 Reference assembly

      Range
      464771..466543
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183492.1NP_014716.1  TPA: Sgo1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014716.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W2D6, O00031, Q08490
      UniProtKB/TrEMBL
      C7GT42
      Conserved Domains (2) summary
      pfam07557
      Location:366390
      Shugoshin_C; Shugoshin C-terminus
      pfam07558
      Location:4387
      Shugoshin_N; Shugoshin N-terminal coiled-coil region