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    CG5805 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 42950, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG5805provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0039223
    Locus tag
    Dmel_CG5805
    See related
    AllianceGenome:FB:FBgn0039223
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG5805
    Summary
    Predicted to enable branched-chain amino acid transmembrane transporter activity. Predicted to be involved in branched-chain amino acid transport. Predicted to be active in mitochondrion. Is expressed in adult head and organism. Orthologous to human SLC25A44 (solute carrier family 25 member 44). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG5805 in Genome Data Viewer
    Location:
    96A22-96A22; 3-85 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (24784552..24787421, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (20610274..20613143, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45650 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Ets96B Neighboring gene Uracil-DNA degrading factor

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Proton-Coupled Monocarboxylate Transporter Hermes Is Necessary for Autophagy during Cell Death. Velentzas PD, et al. Dev Cell, 2018 Nov 5. PMID 30318245, Free PMC Article
    2. Drosophila melanogaster Mitochondrial Carriers: Similarities and Differences with the Human Carriers. Curcio R, et al. Int J Mol Sci, 2020 Aug 22. PMID 32842667, Free PMC Article
    3. Phylogenetic Analysis Guides Transporter Protein Deorphanization: A Case Study of the SLC25 Family of Mitochondrial Metabolite Transporters. Byrne KL, et al. Biomolecules, 2023 Aug 28. PMID 37759714, Free PMC Article
    4. Zinc Detoxification: A Functional Genomics and Transcriptomics Analysis in Drosophila melanogaster Cultured Cells. Mohr SE, et al. G3 (Bethesda), 2018 Feb 2. PMID 29223976, Free PMC Article
    5. Gene expression in a Drosophila model of mitochondrial disease. Fernández-Ayala DJ, et al. PLoS One, 2010 Jan 6. PMID 20066047, Free PMC Article

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables branched-chain amino acid transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables branched-chain amino acid transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in branched-chain amino acid catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in branched-chain amino acid transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG5805-PA
    CG5805-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      24784552..24787421 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001300584.1 → NP_001287513.1  uncharacterized protein Dmel_CG5805, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001287513.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VC40
      Conserved Domains (1) summary
      pfam00153
      Location:46 → 125
      Mito_carr; Mitochondrial carrier protein

    2. NM_143027.4 → NP_651284.1  uncharacterized protein Dmel_CG5805, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651284.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VC40
      Related
      FBpp0084118
      Conserved Domains (1) summary
      pfam00153
      Location:46 → 125
      Mito_carr; Mitochondrial carrier protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VC40 Q9VC40

    Gene LinkOut

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