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    Srprb signal recognition particle receptor, B subunit [ Mus musculus (house mouse) ]

    Gene ID: 20818, updated on 27-Nov-2024

    Summary

    Official Symbol
    Srprbprovided by MGI
    Official Full Name
    signal recognition particle receptor, B subunitprovided by MGI
    Primary source
    MGI:MGI:102964
    See related
    Ensembl:ENSMUSG00000032553 AllianceGenome:MGI:102964
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to enable ubiquitin protein ligase binding activity. Predicted to be involved in protein targeting to ER. Part of signal recognition particle receptor complex. Is expressed in several structures, including bone; brain; cardiovascular system; genitourinary system; and gut. Orthologous to human SRPRB (SRP receptor subunit beta). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in adrenal adult (RPKM 31.7), placenta adult (RPKM 31.4) and 28 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Srprb in Genome Data Viewer
    Location:
    9 F1; 9 55.0 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (103065232..103079264, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (103188033..103202065, complement)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E8309 Neighboring gene predicted gene, 46128 Neighboring gene predicted gene, 51658 Neighboring gene RAB6B, member RAS oncogene family Neighboring gene STARR-positive B cell enhancer ABC_E6799 Neighboring gene transferrin Neighboring gene predicted gene, 53542

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 
    • Gene trapped (1) 
    • Targeted (2) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables ubiquitin protein ligase binding ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasmic microtubule ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasmic microtubule ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in membrane ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    located_in membrane NAS
    Non-traceable Author Statement
    more info
    PubMed 
    part_of signal recognition particle receptor complex EXP
    Inferred from Experiment
    more info
    PubMed 
    part_of signal recognition particle receptor complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of signal recognition particle receptor complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    signal recognition particle receptor subunit beta
    Names
    SR-beta

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_009275.4NP_033301.1  signal recognition particle receptor subunit beta

      See identical proteins and their annotated locations for NP_033301.1

      Status: PROVISIONAL

      Source sequence(s)
      AK030437
      Consensus CDS
      CCDS23450.1
      UniProtKB/Swiss-Prot
      P47758, Q544X9, Q9D872
      UniProtKB/TrEMBL
      Q542X6
      Related
      ENSMUSP00000035157.9, ENSMUST00000035157.10
      Conserved Domains (2) summary
      cd04105
      Location:63268
      SR_beta; Signal recognition particle receptor, beta subunit (SR-beta), together with SR-alpha, forms the heterodimeric signal recognition particle (SRP)
      pfam09439
      Location:60239
      SRPRB; Signal recognition particle receptor beta subunit

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      103065232..103079264 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)