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    XRCC6 X-ray repair cross complementing 6 [ Macaca fascicularis (crab-eating macaque) ]

    Gene ID: 101866663, updated on 3-Dec-2024

    Summary

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    Gene symbol
    XRCC6
    Gene description
    X-ray repair cross complementing 6
    See related
    Ensembl:ENSMFAG00000003352
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca fascicularis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See XRCC6 in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_05 current T2T-MFA8v1.0 (GCF_037993035.1) 10 NC_088384.1 (9949037..10014693, complement)
    102 previous assembly MFA1912RKSv2 (GCF_012559485.2) 10 NC_052264.1 (69673302..69711402, complement)

    Chromosome 10 - NC_088384.1Genomic Context describing neighboring genes Neighboring gene chromosome 10 C22orf46 homolog Neighboring gene U6 spliceosomal RNA Neighboring gene small nuclear ribonucleoprotein 13 Neighboring gene desumoylating isopeptidase 1 Neighboring gene phosphomannomutase 1 Neighboring gene cold shock domain containing C2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Substitution rate and structural divergence of 5'UTR evolution: comparative analysis between human and cynomolgus monkey cDNAs. Osada N, et al. Mol Biol Evol, 2005 Oct. PMID 15944441
    2. Rate of evolution in brain-expressed genes in humans and other primates. Wang HY, et al. PLoS Biol, 2007 Feb. PMID 17194215, Free PMC Article
    3. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA helicase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables damaged DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables double-stranded DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables telomeric DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in double-strand break repair via nonhomologous end joining IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in telomere maintenance IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of Ku70:Ku80 complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    X-ray repair cross-complementing protein 6

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_037993035.1-RS_2024_05

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference T2T-MFA8v1.0

    Genomic

    1. NC_088384.1 Reference T2T-MFA8v1.0

      Range
      9949037..10014693 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_065522085.1 → XP_065378157.1  X-ray repair cross-complementing protein 6

      UniProtKB/TrEMBL
      A0A2K5WAC8, A0A8J8YAA5, G7PFN9, Q4R673

    2. XM_005567141.4 → XP_005567198.1  X-ray repair cross-complementing protein 6

      See identical proteins and their annotated locations for XP_005567198.1

      UniProtKB/TrEMBL
      A0A2K5WAC8, A0A8J8YAA5, G7PFN9, Q4R673
      Conserved Domains (1) summary
      TIGR00578
      Location:26 → 608
      ku70; ATP-dependent DNA helicase II, 70 kDa subunit (ku70)

    3. XM_045363535.2 → XP_045219470.1  X-ray repair cross-complementing protein 6

      UniProtKB/TrEMBL
      A0A2K5WAC8, A0A8J8YAA5, G7PFN9, Q4R673
      Conserved Domains (1) summary
      TIGR00578
      Location:26 → 608
      ku70; ATP-dependent DNA helicase II, 70 kDa subunit (ku70)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001284708.1: Suppressed sequence

      Description
      NM_001284708.1: This RefSeq record was removed as a result of standard genome annotation processing. Contact [email protected] for further information.
    Nucleotide Protein
    Heading Accession and Version

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