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    lir-1 BED-type domain-containing protein;LIn-26 Related [ Caenorhabditis elegans ]

    Gene ID: 174240, updated on 9-Dec-2024

    Summary

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    Official Symbol
    lir-1
    Official Full Name
    BED-type domain-containing protein;LIn-26 Related
    Primary source
    WormBase:WBGene00003044
    Locus tag
    CELE_F18A1.3
    See related
    AllianceGenome:WB:WBGene00003044
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable metal ion binding activity. Is expressed in several structures, including head; intestinal cell; muscle cell; pharynx; and tail. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See lir-1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    3
    Sequence:
    Chromosome: II; NC_003280.10 (7672005..7682363)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene putative replication factor A 73 kDa subunit Neighboring gene C2H2-type domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Transcription factor lin-26 Neighboring gene Receptor L-domain domain-containing protein Neighboring gene Protein pid-1 Neighboring gene Na(+)/H(+) exchanger protein 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A tissue-specific knock-out strategy reveals that lin-26 is required for the formation of the somatic gonad epithelium in Caenorhabditis elegans. den Boer BG, et al. Development, 1998 Aug. PMID 9671593
    2. LIR-1 and PDTF-1 regulate the permeability barrier function of the C. elegans cuticle. Sandhu A, et al. MicroPubl Biol, 2021. PMID 35622525, Free PMC Article
    3. lir-2, lir-1 and lin-26 encode a new class of zinc-finger proteins and are organized in two overlapping operons both in Caenorhabditis elegans and in Caenorhabditis briggsae. Dufourcq P, et al. Genetics, 1999 May. PMID 10224256, Free PMC Article
    4. Genome-wide RNAi. Barstead R. Curr Opin Chem Biol, 2001 Feb. PMID 11166650
    5. RNA interference can target pre-mRNA: consequences for gene expression in a Caenorhabditis elegans operon. Bosher JM, et al. Genetics, 1999 Nov. PMID 10545456, Free PMC Article

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    BED-type domain-containing protein;LIn-26 Related
    NP_001022093.1
    • Confirmed by transcript evidence
    NP_001022094.1
    • Confirmed by transcript evidence
    NP_001022095.1
    • Confirmed by transcript evidence
    NP_001022096.1
    • Confirmed by transcript evidence
    NP_001040765.1
    • Confirmed by transcript evidence
    NP_001293591.1
    • Confirmed by transcript evidence
    NP_001293594.1
    • Confirmed by transcript evidence
    NP_001293595.1
    • Partially confirmed by transcript evidence
    NP_001368340.1
    • Partially confirmed by transcript evidence
    NP_001370917.1
    • Partially confirmed by transcript evidence
    NP_001380148.1
    • Confirmed by transcript evidence
    NP_001380149.1
    • Confirmed by transcript evidence
    NP_001380150.1
    • Partially confirmed by transcript evidence
    NP_001380151.1
    • Partially confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      7672005..7682363
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001026923.4 → NP_001022094.1  LIn-26 Related [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001022094.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5EBR0

    2. NM_001026924.6 → NP_001022095.1  LIn-26 Related [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001022095.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8I7K9

    3. NM_001306662.3 → NP_001293591.1  LIn-26 Related [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001293591.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      U4PFD5

    4. NM_001306665.3 → NP_001293594.1  LIn-26 Related [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001293594.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      U4PMZ1

    5. NM_001026922.7 → NP_001022093.1  LIn-26 Related [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001022093.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9Y050

    6. NM_001026925.4 → NP_001022096.1  LIn-26 Related [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001022096.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2KYA2

    7. NM_001393125.1 → NP_001380150.1  LIn-26 Related [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      U4PS83

    8. NM_001306666.4 → NP_001293595.1  LIn-26 Related [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001293595.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      U4PS88

    9. NM_001393122.1 → NP_001380151.1  LIn-26 Related [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      U4PC65

    10. NM_001393123.1 → NP_001380148.1  LIn-26 Related [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      U4PCI9

    11. NM_001047300.4 → NP_001040765.1  LIn-26 Related [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001040765.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q27GT8

    12. NM_001383895.2 → NP_001370917.1  LIn-26 Related [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      U4PFE1

    13. NM_001381503.1 → NP_001368340.1  LIn-26 Related [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      U4PCJ3

    14. NM_001393126.1 → NP_001380149.1  BED-type domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      U4PMY5
    Nucleotide Protein
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