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    Arf4 ADP ribosylation factor 4 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43823, updated on 17-Dec-2024

    Summary

    Official Symbol
    Arf4provided by FlyBase
    Official Full Name
    ADP ribosylation factor 4provided by FlyBase
    Primary source
    FLYBASE:FBgn0013749
    Locus tag
    Dmel_CG11027
    See related
    AllianceGenome:FB:FBgn0013749
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Arf102E; arf102F; Arf102F; Arf2; ARF2; arf4; Arf5; ARFII; CG1102; CG11027; dARFII; Dmel\CG11027; P40945
    Summary
    Enables enzyme activator activity. Involved in compound eye development. Predicted to be active in cytoplasm and plasma membrane. Is expressed in adult head; adult heart; and organism. Orthologous to several human genes including ARF5 (ADP ribosylation factor 5). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See Arf4 in Genome Data Viewer
    Location:
    102F8-102F8; 4-0 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 4 NC_004353.4 (1124167..1125325)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 4 NC_004353.3 (1144793..1145951)

    Chromosome 4 - NC_004353.4Genomic Context describing neighboring genes Neighboring gene Activin-beta Neighboring gene shaven Neighboring gene Calsyntenin Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Kinesin family member 3C

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables GTP binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables GTPase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables enzyme activator activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in compound eye development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in intracellular protein transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in symbiont entry into host cell HMP PubMed 
    involved_in synaptic vesicle endocytosis TAS
    Traceable Author Statement
    more info
    PubMed 
    involved_in vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    ADP ribosylation factor 4
    Names
    ADP ribosylation factor 102F
    ADP ribosylation factor II
    ADP ribosylation factor at 102F
    Arf4-PA
    Arf4-PB
    CG11027-PA
    CG11027-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004353.4 Reference assembly

      Range
      1124167..1125325
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_079892.3NP_524631.1  ADP ribosylation factor 4, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_524631.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P40945, Q9V499
      UniProtKB/TrEMBL
      L0MNA8
      Related
      FBpp0088256
      Conserved Domains (1) summary
      cl40481
      Location:1180
      YlqF_related_GTPase; Circularly permuted YlqF-related GTPases
    2. NM_001272158.1NP_001259087.1  ADP ribosylation factor 4, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001259087.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P40945, Q9V499
      UniProtKB/TrEMBL
      L0MNA8
      Conserved Domains (1) summary
      cl40481
      Location:1180
      YlqF_related_GTPase; Circularly permuted YlqF-related GTPases