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    CG6048 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 31528, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG6048provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0029827
    Locus tag
    Dmel_CG6048
    See related
    AllianceGenome:FB:FBgn0029827
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG6048; SP108
    Summary
    Predicted to enable serine-type endopeptidase activity. Involved in regulation of terminal button organization. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG6048 in Genome Data Viewer
    Location:
    5C10-5C10; 1-14 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (5952565..5954046)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (5846598..5848079)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene female sterile (1) M3 Neighboring gene Glutamate receptor interacting protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Bowman-Birk inhibitor affects pathways associated with energy metabolism in Drosophila melanogaster. Li HM, et al. Insect Mol Biol, 2010 Jun 1. PMID 20113373
    2. Genomic basis of aging and life-history evolution in Drosophila melanogaster. Remolina SC, et al. Evolution, 2012 Nov. PMID 23106705, Free PMC Article
    3. A genetic screen identifies Tor as an interactor of VAPB in a Drosophila model of amyotrophic lateral sclerosis. Deivasigamani S, et al. Biol Open, 2014 Oct 31. PMID 25361581, Free PMC Article
    4. A transcriptomics assessment of oxygen-temperature interactions reveals novel candidate genes underlying variation in thermal tolerance and survival. Boardman L, et al. J Insect Physiol, 2018 Apr. PMID 29038013
    5. SOD1 activity threshold and TOR signalling modulate VAP(P58S) aggregation via reactive oxygen species-induced proteasomal degradation in a Drosophila model of amyotrophic lateral sclerosis. Chaplot K, et al. Dis Model Mech, 2019 Feb 7. PMID 30635270, Free PMC Article

    See all (29) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables serine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables serine-type endopeptidase activity ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in proteolysis ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    involved_in regulation of terminal button organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG6048-PA
    NP_572282.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      5952565..5954046
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_132054.2 → NP_572282.1  uncharacterized protein Dmel_CG6048 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_572282.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W453
      Related
      FBpp0070828
      Conserved Domains (1) summary
      smart00020
      Location:45 → 284
      Tryp_SPc; Trypsin-like serine protease
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9W453 Q9W453

    Gene LinkOut

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