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    brv1 brivido-1 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40116, updated on 9-Dec-2024

    Summary

    Official Symbol
    brv1provided by FlyBase
    Official Full Name
    brivido-1provided by FlyBase
    Primary source
    FLYBASE:FBgn0036874
    Locus tag
    Dmel_CG9472
    See related
    AllianceGenome:FB:FBgn0036874
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Brivido 1; Brivido1; brv; Brv-1; Brv1; CG9472; CT26822; Dmel\CG9472
    Summary
    Enables stretch-activated, monoatomic cation-selective, calcium channel activity. Involved in cellular response to cold; detection of mechanical stimulus involved in sensory perception of touch; and detection of temperature stimulus involved in thermoception. Predicted to be active in membrane. Is expressed in antennal lobe glomerulus VP3; aristal sensory neuron VP3; sacculus; and second segment of antenna. Orthologous to human PKD1L3 (polycystin 1 like 3, transient receptor potential channel interacting). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See brv1 in Genome Data Viewer
    Location:
    76B3-76B3; 3-45 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (19483826..19486498, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (19476926..19479598, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene hairpin RNA:CR32207 Neighboring gene uncharacterized protein Neighboring gene pseudo Neighboring gene hairpin RNA:CR33940 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables calcium channel activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables calcium channel activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables stretch-activated, monoatomic cation-selective, calcium channel activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    brivido-1
    Names
    CG9472-PA
    brivido
    brv1-PA

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      19483826..19486498 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_140859.2NP_649116.1  brivido-1 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649116.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VVZ8
      Related
      FBpp0074750
      Conserved Domains (1) summary
      pfam08016
      Location:165591
      PKD_channel; Polycystin cation channel