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    CG7724 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39918, updated on 9-Dec-2024

    Summary

    Official Symbol
    CG7724provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0036698
    Locus tag
    Dmel_CG7724
    See related
    AllianceGenome:FB:FBgn0036698
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG7724
    Summary
    Predicted to enable oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor and steroid delta-isomerase activity. Predicted to be involved in steroid biosynthetic process. Is expressed in several structures, including adult head; clypeo-labral primordium; embryonic dorsal epidermis; embryonic epipharynx; and embryonic head epidermis. Human ortholog(s) of this gene implicated in congenital bile acid synthesis defect 1; hypertension; hypospadias; and intrahepatic cholestasis. Orthologous to several human genes including HSD3B1 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1) and HSD3B2 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See CG7724 in Genome Data Viewer
    Location:
    73E5-73E5; 3-45 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (17055613..17058533)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (17048713..17051633)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Troponin C at 73F Neighboring gene rogdi Neighboring gene RNA-binding protein 6 Neighboring gene antisense RNA:CR43433 Neighboring gene AFG3 like matrix AAA peptidase subunit 2

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    uncharacterized protein
    Names
    CG7724-PA
    NP_648957.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      17055613..17058533
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_140700.3NP_648957.1  uncharacterized protein Dmel_CG7724 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648957.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VVE3
      Related
      FBpp0075044
      Conserved Domains (2) summary
      COG0451
      Location:10356
      WcaG; Nucleoside-diphosphate-sugar epimerase [Cell wall/membrane/envelope biogenesis]
      cl21454
      Location:8381
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins