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    BIN1 bridging integrator 1 [ Bos taurus (domestic cattle) ]

    Gene ID: 614576, updated on 30-Jan-2025

    Summary

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    Official Symbol
    BIN1provided by VGNC
    Official Full Name
    bridging integrator 1provided by VGNC
    Primary source
    VGNC:VGNC:26497
    See related
    BGD:BT25620; EnsemblRapid:ENSBTAG00070002558
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
    NEW
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    Genomic context

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    See BIN1 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 2 NC_037329.1 (5418320..5475073)

    Chromosome 2 - NC_037329.1Genomic Context describing neighboring genes Neighboring gene large ribosomal subunit protein eL6-like Neighboring gene histone H2A type 1-B Neighboring gene microRNA mir-2350 Neighboring gene uncharacterized LOC132342935 Neighboring gene serine protease 58

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037329.1 Chromosome 2 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC128846

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables phospholipid binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables tau protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of endocytosis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in synaptic vesicle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    myc box-dependent-interacting protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001046541.1 → NP_001040006.1  myc box-dependent-interacting protein 1

      See identical proteins and their annotated locations for NP_001040006.1

      Status: PROVISIONAL

      Source sequence(s)
      BC105557
      UniProtKB/TrEMBL
      A0A3Q1MU19, Q2KJ23
      Conserved Domains (2) summary
      cd07611
      Location:31 → 241
      BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
      cd12139
      Location:361 → 432
      SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037329.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      5418320..5475073
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_010801800.4 → XP_010800102.1  myc box-dependent-interacting protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A3Q1LV21
      Conserved Domains (2) summary
      cd07611
      Location:31 → 272
      BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
      cd12139
      Location:530 → 601
      SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2

    2. XM_010801803.4 → XP_010800105.1  myc box-dependent-interacting protein 1 isoform X4

      UniProtKB/TrEMBL
      A0A3Q1M808
      Related
      ENSBTAP00070003490.1, ENSBTAT00070006020.1
      Conserved Domains (2) summary
      cd07611
      Location:31 → 272
      BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
      cd12139
      Location:486 → 557
      SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2

    3. XM_010801805.4 → XP_010800107.1  myc box-dependent-interacting protein 1 isoform X8

      UniProtKB/TrEMBL
      A0A3Q1M808
      Conserved Domains (2) summary
      cd12139
      Location:450 → 521
      SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2
      cl12013
      Location:31 → 272
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

    4. XM_010801806.4 → XP_010800108.1  myc box-dependent-interacting protein 1 isoform X9

      UniProtKB/TrEMBL
      A0A3Q1M808
      Conserved Domains (2) summary
      cd07611
      Location:31 → 272
      BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
      cd12139
      Location:443 → 514
      SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2

    5. XM_010801809.4 → XP_010800111.1  myc box-dependent-interacting protein 1 isoform X16

      UniProtKB/TrEMBL
      A0A3Q1MU19
      Conserved Domains (2) summary
      cd12139
      Location:407 → 478
      SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2
      cl12013
      Location:31 → 272
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

    6. XM_024977732.2 → XP_024833500.1  myc box-dependent-interacting protein 1 isoform X20

      UniProtKB/TrEMBL
      A0A3Q1M026
      Conserved Domains (2) summary
      cd12139
      Location:384 → 455
      SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2
      cl12013
      Location:31 → 272
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

    7. XM_005202217.5 → XP_005202274.1  myc box-dependent-interacting protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A3Q1LV21, E1BNG8
      Related
      ENSBTAP00070003485.1, ENSBTAT00070006009.1
      Conserved Domains (3) summary
      cd07611
      Location:31 → 272
      BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
      cd12139
      Location:515 → 586
      SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2
      cl26386
      Location:372 → 513
      DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III

    8. XM_024977693.2 → XP_024833461.1  myc box-dependent-interacting protein 1 isoform X11

      UniProtKB/TrEMBL
      A0A3Q1M808
      Conserved Domains (2) summary
      cd12139
      Location:435 → 506
      SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2
      cl12013
      Location:31 → 272
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

    9. XM_005202222.5 → XP_005202279.1  myc box-dependent-interacting protein 1 isoform X12

      UniProtKB/TrEMBL
      A0A3Q1M808, A0A3Q1NHQ0
      Conserved Domains (3) summary
      cd07611
      Location:31 → 272
      BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
      cd12139
      Location:428 → 499
      SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2
      cl26386
      Location:281 → 426
      DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III

    10. XM_024977722.2 → XP_024833490.1  myc box-dependent-interacting protein 1 isoform X19

      UniProtKB/TrEMBL
      A0A3Q1MU19, A0A3Q1NGS3
      Conserved Domains (2) summary
      cd12139
      Location:392 → 463
      SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2
      cl12013
      Location:31 → 272
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

    11. XM_024977745.2 → XP_024833513.1  myc box-dependent-interacting protein 1 isoform X22

      UniProtKB/TrEMBL
      A0A3Q1M026
      Conserved Domains (2) summary
      cd12139
      Location:369 → 440
      SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2
      cl12013
      Location:31 → 272
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

    12. XM_010801801.3 → XP_010800103.1  myc box-dependent-interacting protein 1 isoform X3

      UniProtKB/TrEMBL
      A0A3Q1LV21
      Conserved Domains (2) summary
      cd07611
      Location:31 → 241
      BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
      cd12139
      Location:499 → 570
      SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2

    13. XM_005202220.4 → XP_005202277.1  myc box-dependent-interacting protein 1 isoform X7

      UniProtKB/TrEMBL
      A0A3Q1M808
      Conserved Domains (3) summary
      cd07611
      Location:31 → 241
      BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
      cd12139
      Location:455 → 526
      SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2
      cl25496
      Location:301 → 480
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)

    14. XM_005202223.4 → XP_005202280.1  myc box-dependent-interacting protein 1 isoform X14

      UniProtKB/TrEMBL
      A0A3Q1M026, A0A3Q1N5F9
      Related
      ENSBTAP00070003452.1, ENSBTAT00070005940.1
      Conserved Domains (3) summary
      cd07611
      Location:31 → 241
      BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
      cd12139
      Location:419 → 490
      SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2
      cl25496
      Location:301 → 400
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)

    15. XM_005202224.4 → XP_005202281.1  myc box-dependent-interacting protein 1 isoform X15

      UniProtKB/TrEMBL
      A0A3Q1M026
      Conserved Domains (3) summary
      cd07611
      Location:31 → 241
      BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
      cd12139
      Location:412 → 483
      SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2
      cl26386
      Location:273 → 410
      DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III

    16. XM_005202227.3 → XP_005202284.1  myc box-dependent-interacting protein 1 isoform X21

      UniProtKB/TrEMBL
      A0A3Q1MU19
      Related
      ENSBTAP00070003509.1, ENSBTAT00070006054.1
      Conserved Domains (2) summary
      cd07611
      Location:31 → 241
      BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
      cd12139
      Location:376 → 447
      SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2

    17. XM_015474474.2 → XP_015329960.1  myc box-dependent-interacting protein 1 isoform X23

      UniProtKB/TrEMBL
      A0A3Q1M026
      Related
      ENSBTAP00070003442.1, ENSBTAT00070005924.1
      Conserved Domains (2) summary
      cd07611
      Location:31 → 241
      BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
      cd12139
      Location:353 → 424
      SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2

    18. XM_005202218.4 → XP_005202275.1  myc box-dependent-interacting protein 1 isoform X5

      UniProtKB/TrEMBL
      A0A3Q1LV21
      Conserved Domains (3) summary
      cd07611
      Location:31 → 241
      BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
      cd12139
      Location:484 → 555
      SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2
      cl26386
      Location:341 → 482
      DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III

    19. XM_005202221.4 → XP_005202278.1  myc box-dependent-interacting protein 1 isoform X10

      UniProtKB/TrEMBL
      A0A3Q1M808, F6R9I4
      Conserved Domains (3) summary
      cd07611
      Location:31 → 241
      BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
      cd12139
      Location:440 → 511
      SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2
      cl25496
      Location:286 → 465
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)

    20. XM_005202225.4 → XP_005202282.1  myc box-dependent-interacting protein 1 isoform X17

      UniProtKB/TrEMBL
      A0A3Q1M026
      Conserved Domains (3) summary
      cd07611
      Location:31 → 241
      BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
      cd12139
      Location:404 → 475
      SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2
      cl25496
      Location:286 → 385
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)

    21. XM_005202226.5 → XP_005202283.1  myc box-dependent-interacting protein 1 isoform X18

      UniProtKB/TrEMBL
      A0A3Q1M026
      Related
      ENSBTAP00070003497.1, ENSBTAT00070006032.1
      Conserved Domains (3) summary
      cd07611
      Location:31 → 241
      BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
      cd12139
      Location:397 → 468
      SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2
      cl26386
      Location:250 → 395
      DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III

    22. XM_005202228.3 → XP_005202285.1  myc box-dependent-interacting protein 1 isoform X24

      See identical proteins and their annotated locations for XP_005202285.1

      UniProtKB/TrEMBL
      A0A3Q1M026
      Conserved Domains (2) summary
      cd07611
      Location:31 → 241
      BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
      cd12139
      Location:338 → 409
      SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2

    23. XM_010801804.3 → XP_010800106.1  myc box-dependent-interacting protein 1 isoform X6

      UniProtKB/TrEMBL
      A0A3Q1LV21
      Conserved Domains (2) summary
      cd12139
      Location:456 → 527
      SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2
      cl12013
      Location:1 → 198
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

    24. XM_010801807.3 → XP_010800109.1  myc box-dependent-interacting protein 1 isoform X13

      UniProtKB/TrEMBL
      A0A3Q1ML09
      Conserved Domains (2) summary
      cd12139
      Location:425 → 496
      SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2
      cl12013
      Location:1 → 167
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

    25. XM_024977754.2 → XP_024833522.1  myc box-dependent-interacting protein 1 isoform X25

      UniProtKB/TrEMBL
      A0A3Q1ML09
      Conserved Domains (2) summary
      cd07611
      Location:7 → 217
      BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
      cd12139
      Location:314 → 385
      SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2
    Nucleotide Protein Strain
    Heading Accession and Version

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