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    MIX14 Mix14p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 851595, updated on 9-Dec-2024

    Summary

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    Official Symbol
    MIX14
    Official Full Name
    Mix14p
    Primary source
    SGD:S000002438
    Locus tag
    YDR031W
    See related
    AllianceGenome:SGD:S000002438; FungiDB:YDR031W; VEuPathDB:YDR031W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    MIC14
    Summary
    Involved in aerobic respiration. Located in mitochondrial intermembrane space. Orthologous to human CHCHD5 (coiled-coil-helix-coiled-coil-helix domain containing 5). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See MIX14 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    1
    Sequence:
    Chromosome: IV; NC_001136.10 (503498..503863)

    Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Rad28p Neighboring gene flavodoxin-like fold family protein Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001136.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Novel mitochondrial intermembrane space proteins as substrates of the MIA import pathway. Gabriel K, et al. J Mol Biol, 2007 Jan 19. PMID 17095012
    2. Systematic analysis of the twin cx(9)c protein family. Longen S, et al. J Mol Biol, 2009 Oct 23. PMID 19703468
    3. Yeast Saccharomyces cerevisiae adiponectin receptor homolog Izh2 is involved in the regulation of zinc, phospholipid and pH homeostasis. Mattiazzi Ušaj M, et al. Metallomics, 2015 Sep. PMID 26067383
    4. Mitochondrial heat shock protein (Hsp) 70 and Hsp10 cooperate in the formation of Hsp60 complexes. Böttinger L, et al. J Biol Chem, 2015 May 1. PMID 25792736, Free PMC Article
    5. Quantitative variations of the mitochondrial proteome and phosphoproteome during fermentative and respiratory growth in Saccharomyces cerevisiae. Renvoisé M, et al. J Proteomics, 2014 Jun 25. PMID 24769239

    See all (22) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in aerobic respiration IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in cellular respiration IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    is_active_in mitochondrial intermembrane space IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrial intermembrane space IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrial intermembrane space IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    Mix14p
    NP_010314.4
    • Mitochondrial intermembrane space hypothetical protein; required for normal oxygen consumption; contains twin cysteine-x9-cysteine motifs; protein abundance increases in response to DNA replication stress

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001136.10 Reference assembly

      Range
      503498..503863
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180339.3 → NP_010314.4  TPA: Mix14p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_010314.4

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VS15, Q04341, Q07789
      UniProtKB/TrEMBL
      A6ZXZ3, B3LGN5, C7GLW8, C8Z4V1, G2WAD6, N1P644
      Conserved Domains (1) summary
      pfam16860
      Location:12 → 53
      CX9C; CHCH-CHCH-like Cx9C, IMS import disulfide relay-system,
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q04341.1

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