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    Actin-binding FH2 (formin homology 2) family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 818984, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Actin-binding FH2 (formin homology 2) family protein
    Primary source
    TAIR:AT2G43800
    Locus tag
    AT2G43800
    See related
    Araport:AT2G43800
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F18O19.9
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    Genomic context

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    Location:
    chromosome: 2
    Exon count:
    4
    Sequence:
    Chromosome: 2; NC_003071.7 (18145439..18149031)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene MAP kinase 6 Neighboring gene corepressor Neighboring gene Small nuclear ribonucleoprotein family protein Neighboring gene UDP-glucosyltransferase 74F2 Neighboring gene miscRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis formin 2 regulates cell-to-cell trafficking by capping and stabilizing actin filaments at plasmodesmata. Diao M, et al. Elife, 2018 Aug 16. PMID 30113309, Free PMC Article
    2. Formin homology 2 domains occur in multiple contexts in angiosperms. Cvrcková F, et al. BMC Genomics, 2004 Jul 15. PMID 15256004, Free PMC Article
    3. Formins: intermediates in signal-transduction cascades that affect cytoskeletal reorganization. Deeks MJ, et al. Trends Plant Sci, 2002 Nov. PMID 12417149
    4. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    General gene information

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    NM_129942.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables actin binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables actin filament binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in actin nucleation IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within barbed-end actin filament capping IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within plasmodesmata-mediated intercellular transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    colocalizes_with plasmodesma IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Actin-binding FH2 (formin homology 2) family protein
    NP_181908.1
    • Actin-binding FH2 (formin homology 2) family protein; FUNCTIONS IN: actin binding; INVOLVED IN: cellular component organization, actin cytoskeleton organization; LOCATED IN: plasma membrane; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Actin-binding FH2/DRF autoregulatory (InterPro:IPR003104), Actin-binding FH2 (InterPro:IPR015425); BEST Arabidopsis thaliana protein match is: formin homology 1 (TAIR:AT3G25500.1); Has 24262 Blast hits to 14906 proteins in 847 species: Archae - 39; Bacteria - 2066; Metazoa - 8621; Fungi - 3513; Plants - 5949; Viruses - 1021; Other Eukaryotes - 3053 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      18145439..18149031
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_129942.3 → NP_181908.1  Actin-binding FH2 (formin homology 2) family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_181908.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O22824
      UniProtKB/TrEMBL
      A0A178VS83, A0A5S9X7A1
      Conserved Domains (1) summary
      pfam02181
      Location:438 → 839
      FH2; Formin Homology 2 Domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O22824.1

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