DIS1 Actin-like ATPase superfamily protein [Arabidopsis thaliana (thale cress)] - Gene

Summary

Official Symbol: DIS1
Official Full Name: Actin-like ATPase superfamily protein
Primary source: TAIR:AT1G13180
Locus tag: AT1G13180
See related: Araport:AT1G13180
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: ACTIN-RELATED PROTEIN 3; ARABIDOPSIS THALIANA ACTIN-RELATED PROTEIN 3; ARP3; ATARP3; DISTORTED TRICHOMES 1; F3F19.20; F3F19_20
Summary: Mutant has defect in trichome cell expansion and actin organization resulting in a distorted trichome phenotype.
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Chromosome 1 - NC_003070.9 Genomic Context describing neighboring genes

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role in amyloplast sedimentation and polar auxin transport in root gravitropism
Title: The role of Arabidopsis Actin-Related Protein 3 in amyloplast sedimentation and polar auxin transport in root gravitropism.
Arp2/3 complex regulates mitochondrial-dependent Ca(2+) signaling in response to salt stress.
Title: The actin-related Protein2/3 complex regulates mitochondrial-associated calcium signaling during salt stress in Arabidopsis.
The work indicates that regulation of actin reassembly through ARP2/3 complex activity is crucial for stomatal regulation.
Title: The ARP2/3 complex mediates guard cell actin reorganization and stomatal movement in Arabidopsis.
The rapid growth of roots in the light requires a functional ARP2/3-SCAR complex.
Title: SCAR mediates light-induced root elongation in Arabidopsis through photoreceptors and proteasomes.
Differences among SCARs in mRNA levels and the biochemical efficiency of ARP2/3 activation may explain the functional contributions of individual genes
Title: Arabidopsis SCARs function interchangeably to meet actin-related protein 2/3 activation thresholds during morphogenesis.
BRK1 is required for accumulation of SCAR1 protein in vivo, potentially explaining the apparently essential role of BRK1 in ARP2/3 complex function
Title: BRICK1/HSPC300 functions with SCAR and the ARP2/3 complex to regulate epidermal cell shape in Arabidopsis.

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

NM_101188.3

Process	Evidence Code	Pubs
acts_upstream_of_or_within actin filament organization	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within cell morphogenesis	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within multidimensional cell growth	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within trichome morphogenesis	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
part_of Arp2/3 protein complex	TAS Traceable Author Statement more info	PubMed
located_in cytoplasm	ISM Inferred from Sequence Model more info

NP_172777.1

DISTORTED TRICHOMES 1 (DIS1); FUNCTIONS IN: actin binding, structural constituent of cytoskeleton, ATP binding; INVOLVED IN: actin filament organization, multidimensional cell growth, cell morphogenesis, trichome morphogenesis; LOCATED IN: Arp2/3 protein complex; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Actin/actin-like (InterPro:IPR004000), Actin-related protein 3 (InterPro:IPR015623); BEST Arabidopsis thaliana protein match is: Actin-like ATPase superfamily protein (TAIR:AT2G42100.1); Has 12406 Blast hits to 12242 proteins in 2483 species: Archae - 6; Bacteria - 5; Metazoa - 5339; Fungi - 3178; Plants - 1454; Viruses - 2; Other Eukaryotes - 2422 (source: NCBI BLink).

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