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    NCK2 NCK adaptor protein 2 [ Pteropus vampyrus (large flying fox) ]

    Gene ID: 105298753, updated on 30-Mar-2024

    Summary

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    Gene symbol
    NCK2
    Gene description
    NCK adaptor protein 2
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Pteropus vampyrus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yinpterochiroptera; Pteropodoidea; Pteropodidae; Pteropodinae; Pteropus
    Orthologs
    human mouse all
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    Genomic context

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    See NCK2 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    101 current Pvam_2.0 (GCF_000151845.1) Unplaced Scaffold NW_011888941.1 (3977346..4001316)

    NW_011888941.1Genomic Context describing neighboring genes Neighboring gene 5S ribosomal RNA Neighboring gene cytoplasmic protein NCK2-like Neighboring gene 5S ribosomal RNA Neighboring gene 60S ribosomal protein L9 pseudogene Neighboring gene 5S ribosomal RNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_011888941 Unplaced Scaffold Reference Pvam_2.0

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of PERK-mediated unfolded protein response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of translation in response to endoplasmic reticulum stress IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cytoplasmic protein NCK2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Pteropus vampyrus Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Pvam_2.0

    Genomic

    1. NW_011888941.1 Reference Pvam_2.0

      Range
      3977346..4001316
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011370155.2 → XP_011368457.1  cytoplasmic protein NCK2

      UniProtKB/TrEMBL
      A0A6P3QT03
      Conserved Domains (3) summary
      cd10409
      Location:228 → 325
      SH2_Nck2; Src homology 2 (SH2) domain found in Nck
      cd11902
      Location:59 → 113
      SH3_Nck2_2; Second Src Homology 3 domain of Nck2 adaptor protein
      cd11903
      Location:143 → 201
      SH3_Nck2_3; Third Src Homology 3 domain of Nck2 adaptor protein
    Nucleotide Protein
    Heading Accession and Version

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