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    Fancd2os Fancd2 opposite strand [ Mus musculus (house mouse) ]

    Gene ID: 70979, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Fancd2osprovided by MGI
    Official Full Name
    Fancd2 opposite strandprovided by MGI
    Primary source
    MGI:MGI:1918229
    See related
    Ensembl:ENSMUSG00000033963 AllianceGenome:MGI:1918229
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    4931417G12Rik
    Summary
    Orthologous to human FANCD2OS (FANCD2 opposite strand). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in testis adult (RPKM 7.7) and kidney adult (RPKM 0.2) See more
    Orthologs
    human all
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    Genomic context

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    See Fancd2os in Genome Data Viewer
    Location:
    6 E3; 6 52.8 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (113573722..113577735, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (113596761..113600715, complement)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene Fanconi anemia, complementation group D2 Neighboring gene predicted gene, 46971 Neighboring gene STARR-seq mESC enhancer starr_17043 Neighboring gene predicted gene, 38874 Neighboring gene STARR-seq mESC enhancer starr_17044 Neighboring gene BRICK1, SCAR/WAVE actin-nucleating complex subunit Neighboring gene von Hippel-Lindau tumor suppressor

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Relaxed negative selection in germinal centers and impaired affinity maturation in bcl-xL transgenic mice. Takahashi Y, et al. J Exp Med, 1999 Aug 2. PMID 10430628, Free PMC Article
    2. Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method. Piao Y, et al. Genome Res, 2001 Sep. PMID 11544199, Free PMC Article
    3. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
    4. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    5. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    FANCD2 opposite strand protein
    Names
    Fanconi anemia group D2 protein opposite strand transcript protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_027633.3 → NP_081909.2  FANCD2 opposite strand protein

      See identical proteins and their annotated locations for NP_081909.2

      Status: VALIDATED

      Source sequence(s)
      AC153589, AK016461
      Consensus CDS
      CCDS20427.1
      UniProtKB/Swiss-Prot
      Q80XT0, Q80Y40, Q9D4K4
      UniProtKB/TrEMBL
      A0A0R4J1W5
      Related
      ENSMUSP00000035316.5, ENSMUST00000035870.5
      Conserved Domains (1) summary
      pfam15124
      Location:3 → 178
      FANCD2OS; FANCD2 opposite strand protein

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      113573722..113577735 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036152304.1 → XP_036008197.1  FANCD2 opposite strand protein isoform X2

      UniProtKB/Swiss-Prot
      Q80XT0, Q80Y40, Q9D4K4
      Conserved Domains (1) summary
      pfam15124
      Location:25 → 200
      FANCD2OS; FANCD2 opposite strand protein

    2. XM_006506608.4 → XP_006506671.1  FANCD2 opposite strand protein isoform X2

      UniProtKB/Swiss-Prot
      Q80XT0, Q80Y40, Q9D4K4
      Conserved Domains (1) summary
      pfam15124
      Location:25 → 200
      FANCD2OS; FANCD2 opposite strand protein

    3. XM_006506610.4 → XP_006506673.1  FANCD2 opposite strand protein isoform X3

      See identical proteins and their annotated locations for XP_006506673.1

      UniProtKB/Swiss-Prot
      Q80XT0, Q80Y40, Q9D4K4
      UniProtKB/TrEMBL
      A0A0R4J1W5
      Conserved Domains (1) summary
      pfam15124
      Location:3 → 178
      FANCD2OS; FANCD2 opposite strand protein

    4. XM_006506609.4 → XP_006506672.1  FANCD2 opposite strand protein isoform X3

      See identical proteins and their annotated locations for XP_006506672.1

      UniProtKB/Swiss-Prot
      Q80XT0, Q80Y40, Q9D4K4
      UniProtKB/TrEMBL
      A0A0R4J1W5
      Conserved Domains (1) summary
      pfam15124
      Location:3 → 178
      FANCD2OS; FANCD2 opposite strand protein

    5. XM_017321739.2 → XP_017177228.1  FANCD2 opposite strand protein isoform X1

      UniProtKB/Swiss-Prot
      Q80XT0, Q80Y40, Q9D4K4
      Conserved Domains (1) summary
      pfam15124
      Location:35 → 210
      FANCD2OS; FANCD2 opposite strand protein
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9D4K4.1 GenPept UniProtKB/Swiss-Prot:Q9D4K4

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