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    PPIL2 peptidylprolyl isomerase like 2 [ Bos taurus (domestic cattle) ]

    Gene ID: 511467, updated on 30-Jan-2025

    Summary

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    Official Symbol
    PPIL2provided by VGNC
    Official Full Name
    peptidylprolyl isomerase like 2provided by VGNC
    Primary source
    VGNC:VGNC:33202
    See related
    BGD:BT29069; EnsemblRapid:ENSBTAG00070019512
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See PPIL2 in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 17 NC_037344.1 (72082606..72100524, complement)

    Chromosome 17 - NC_037344.1Genomic Context describing neighboring genes Neighboring gene large ribosomal subunit protein eL39-like Neighboring gene mitogen-activated protein kinase 1 Neighboring gene yippee like 1 Neighboring gene uncharacterized LOC101905136 Neighboring gene microRNA mir-130b

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037344.1 Chromosome 17 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC134547

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables peptidyl-prolyl cis-trans isomerase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ubiquitin protein ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein folding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein peptidyl-prolyl isomerization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein polyubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of catalytic step 2 spliceosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    RING-type E3 ubiquitin-protein ligase PPIL2
    Names
    peptidylprolyl isomerase (cyclophilin)-like 2
    NP_001033170.1
    XP_024832941.1
    XP_024832942.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001038081.1 → NP_001033170.1  RING-type E3 ubiquitin-protein ligase PPIL2

      See identical proteins and their annotated locations for NP_001033170.1

      Status: PROVISIONAL

      Source sequence(s)
      BC111254
      UniProtKB/TrEMBL
      A0A3Q1MA12, Q2T9V1
      Related
      ENSBTAP00070026577.1, ENSBTAT00070044126.1
      Conserved Domains (2) summary
      smart00504
      Location:42 → 101
      Ubox; Modified RING finger domain
      cd01923
      Location:313 → 472
      cyclophilin_RING; cyclophilin_RING: cyclophilin-type peptidylprolyl cis- trans isomerases (cyclophilins) having a modified RING finger domain. This group includes the nuclear proteins, Human hCyP-60 and Caenorhabditis elegans MOG-6 which, compared to the archetypal ...

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037344.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      72082606..72100524 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024977173.2 → XP_024832941.1  RING-type E3 ubiquitin-protein ligase PPIL2 isoform X1

      UniProtKB/TrEMBL
      A0A3Q1MA12
      Related
      ENSBTAP00070026584.1, ENSBTAT00070044142.1
      Conserved Domains (2) summary
      cd01923
      Location:292 → 451
      cyclophilin_RING; cyclophilin_RING: cyclophilin-type peptidylprolyl cis- trans isomerases (cyclophilins) having a modified RING finger domain. This group includes the nuclear proteins, Human hCyP-60 and Caenorhabditis elegans MOG-6 which, compared to the archetypal ...
      cl17238
      Location:38 → 89
      RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

    2. XM_024977174.2 → XP_024832942.1  RING-type E3 ubiquitin-protein ligase PPIL2 isoform X2

      UniProtKB/TrEMBL
      A0A3Q1NGY0
      Related
      ENSBTAP00070026593.1, ENSBTAT00070044156.1
      Conserved Domains (3) summary
      cd01923
      Location:281 → 440
      cyclophilin_RING; cyclophilin_RING: cyclophilin-type peptidylprolyl cis- trans isomerases (cyclophilins) having a modified RING finger domain. This group includes the nuclear proteins, Human hCyP-60 and Caenorhabditis elegans MOG-6 which, compared to the archetypal ...
      cd16663
      Location:38 → 110
      RING-Ubox_PPIL2; U-box domain, a modified RING finger, found in peptidyl-prolyl cis-trans isomerase-like 2 (PPIL2) and similar proteins
      cl17238
      Location:100 → 159
      RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain
    Nucleotide Protein Strain
    Heading Accession and Version

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