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    IL1B interleukin 1 beta [ Bubalus bubalis (water buffalo) ]

    Gene ID: 102396262, updated on 10-Mar-2024

    Summary

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    Gene symbol
    IL1B
    Gene description
    interleukin 1 beta
    See related
    EnsemblRapid:ENSBALG00030024728
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bubalus bubalis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bubalus
    Also known as
    IL-1b
    Orthologs
    human mouse all
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    Genomic context

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    See IL1B in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    103 current NDDB_SH_1 (GCF_019923935.1) 12 NC_059168.1 (46075305..46083724, complement)
    102 previous assembly NDDB_DH_1 (GCF_019923925.1) 12 NC_058354.1 (46064180..46072599, complement)

    Chromosome 12 - NC_059168.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC123328521 Neighboring gene enhancer of rudimentary homolog Neighboring gene interleukin 37 Neighboring gene interleukin 36 gamma Neighboring gene interleukin 36 alpha

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. IGF-1 attenuates LPS induced pro-inflammatory cytokines expression in buffalo (Bubalus bubalis) granulosa cells. Onnureddy K, et al. Mol Immunol, 2015 Mar. PMID 25433435
    2. Molecular cloning, sequencing and phylogenetic analysis of inflammatory cytokines of swamp type buffalo contrasting with other bubaline breeds. Mingala CN, et al. Comp Immunol Microbiol Infect Dis, 2007 Mar. PMID 17224182
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables cytokine activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables interleukin-1 receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cellular response to lipopolysaccharide IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cytokine-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in inflammatory response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of gene expression IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of immature T cell proliferation in thymus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of nitric-oxide synthase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    interleukin-1 beta

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001290898.1 → NP_001277827.1  interleukin-1 beta

      See identical proteins and their annotated locations for NP_001277827.1

      Status: PROVISIONAL

      Source sequence(s)
      AB246787
      UniProtKB/TrEMBL
      Q6R498
      Related
      ENSBALP00030046989.1, ENSBALT00030069423.1
      Conserved Domains (2) summary
      smart00125
      Location:116 → 262
      IL1; Interleukin-1 homologues
      pfam02394
      Location:1 → 100
      IL1_propep; Interleukin-1 propeptide

    RefSeqs of Annotated Genomes: Bubalus bubalis Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NDDB_SH_1 Primary Assembly

    Genomic

    1. NC_059168.1 Reference NDDB_SH_1 Primary Assembly

      Range
      46075305..46083724 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_025260560.3 → XP_025116345.1  interleukin-1 beta isoform X1

      UniProtKB/TrEMBL
      Q6R498
      Conserved Domains (2) summary
      smart00125
      Location:116 → 262
      IL1; Interleukin-1 homologues
      pfam02394
      Location:1 → 100
      IL1_propep; Interleukin-1 propeptide
    Nucleotide Protein
    Heading Accession and Version

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