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    gspL Type II secretion system protein GspL [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 947842, updated on 3-Dec-2024

    Summary

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    Official Symbol
    gspL
    Official Full Name
    Type II secretion system protein GspL
    Primary source
    ECOCYC:G7711
    Locus tag
    b3333
    See related
    ASAP:ABE-0010896
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3320; yheK
    Summary
    A divergon is a regulon comprised of two adjacent divergent operons or genes. [More information is available at EcoGene: EG12895]. In Escherichia coli, gspL is a member of an operon of genes (gspC-O) which are not normally expressed but are homologous to those encoding the secreton, or type II secretion machinery in Klebsiella oxytoca and Aeromonase hydrophila, among others . [More information is available at EcoCyc: G7711].
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    Genomic context

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    Sequence:
    NC_000913.3 (3463922..3465085)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene Type II secretion system protein GspH Neighboring gene Type II secretion system protein GspI Neighboring gene Type II secretion system protein GspJ Neighboring gene Type II secretion system protein GspK Neighboring gene Type II secretion system protein GspM Neighboring gene Type II secretion system prepilin peptidase Neighboring gene bacterioferritin

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. [Construction and characterization of a gspL mutant of avian pathogenic Escherichia coli]. Fan G, et al. Wei Sheng Wu Xue Bao, 2015 Jan 4. PMID 25958687
    2. Biology of type II secretion. Sandkvist M. Mol Microbiol, 2001 Apr. PMID 11309111
    3. Type IV-like pili formed by the type II secreton: specificity, composition, bundling, polar localization, and surface presentation of peptides. Vignon G, et al. J Bacteriol, 2003 Jun. PMID 12754241, Free PMC Article
    4. Protein secretion in Escherichia coli K-12: dead or alive? Pugsley AP, et al. Cell Mol Life Sci, 1998 Apr. PMID 9614971, Free PMC Article
    5. Involvement of the twin-arginine translocation system in protein secretion via the type II pathway. Voulhoux R, et al. EMBO J, 2001 Dec 3. PMID 11726509, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The deletion of gspL gene abated the ability of adhesion and invasion and enhance the virulence.
      Title: [Construction and characterization of a gspL mutant of avian pathogenic Escherichia coli].
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Process Evidence Code Pubs
    involved_in protein secretion by the type II secretion system IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in Gram-negative-bacterium-type cell wall IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    part_of type II protein secretion system complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Type II secretion system protein GspL

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3463922..3465085
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417792.2 Type II secretion system protein GspL [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417792.2

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A1X3JBP5
      Conserved Domains (1) summary
      COG3297
      Location:1 → 385
      PulL; Type II secretory pathway, component PulL [Intracellular trafficking, secretion, and vesicular transport]
    Nucleotide Protein
    Heading Accession and Version

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