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    ghrB glyoxylate reductase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948074, updated on 17-Dec-2024

    Summary

    Official Symbol
    ghrB
    Official Full Name
    glyoxylate reductase
    Primary source
    ECOCYC:EG12272
    Locus tag
    b3553
    See related
    ASAP:ABE-0011604
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3540; tkrA; yiaE
    Summary
    AFMB Structural Genomics target Number 33 (http://afmb.cnrs-mrs.fr/article171.html). [More information is available at EcoGene: EG12272].
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    Genomic context

    Sequence:
    NC_000913.3 (3717310..3718284)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene peptidyl-lysine N-acetyltransferase YiaC Neighboring gene biotin sulfoxide reductase Neighboring gene PF13488 family lipoprotein YiaD Neighboring gene DUF3053 domain-containing protein YiaF Neighboring gene putative DNA-binding transcriptional regulator YiaG

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables NAD binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables gluconate 2-dehydrogenase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables gluconate 2-dehydrogenase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables glyoxylate reductase (NADPH) activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables glyoxylate reductase (NADPH) activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables glyoxylate reductase (NADPH) activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables hydroxypyruvate reductase (NADH) activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables hydroxypyruvate reductase (NADPH) activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables hydroxypyruvate reductase [NAD(P)H] activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables hydroxypyruvate reductase [NAD(P)H] activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in D-gluconate metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within ketogluconate catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    glyoxylate reductase
    NP_418009.2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3717310..3718284
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_418009.2 glyoxylate reductase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_418009.2

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A2X1N5B3
      Conserved Domains (1) summary
      PRK15409
      Location:1323
      PRK15409; glyoxylate/hydroxypyruvate reductase GhrB