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    Y50E8A.6 Glycerol-3-phosphate dehydrogenase [ Caenorhabditis elegans ]

    Gene ID: 190107, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Y50E8A.6
    Official Full Name
    Glycerol-3-phosphate dehydrogenase
    Primary source
    WormBase:WBGene00013049
    Locus tag
    CELE_Y50E8A.6
    See related
    AllianceGenome:WB:WBGene00013049
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable glycerol-3-phosphate dehydrogenase (quinone) activity. Predicted to be involved in glycerol-3-phosphate metabolic process. Predicted to be part of glycerol-3-phosphate dehydrogenase (FAD) complex. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human GPD2 (glycerol-3-phosphate dehydrogenase 2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See Y50E8A.6 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    6
    Sequence:
    Chromosome: V; NC_003283.11 (14738503..14741333, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Protein quiver Neighboring gene pseudo Neighboring gene pseudo Neighboring gene ncRNA Neighboring gene Lipase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables glycerol-3-phosphate dehydrogenase (quinone) activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in glycerol-3-phosphate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in organophosphate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in phosphate-containing compound metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Glycerol-3-phosphate dehydrogenase
    NP_506640.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      14738503..14741333 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_074239.5 → NP_506640.2  Glycerol-3-phosphate dehydrogenase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_506640.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9NAF2
      Conserved Domains (2) summary
      PLN02464
      Location:14 → 578
      PLN02464; glycerol-3-phosphate dehydrogenase
      pfam16901
      Location:452 → 578
      DAO_C; C-terminal domain of alpha-glycerophosphate oxidase
    Nucleotide Protein
    Heading Accession and Version

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