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    ssr2 signal sequence receptor, beta [ Danio rerio (zebrafish) ]

    Gene ID: 83414, updated on 2-Nov-2024

    Summary

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    Official Symbol
    ssr2provided by ZNC
    Official Full Name
    signal sequence receptor, betaprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-010413-1
    See related
    Ensembl:ENSDARG00000005230 AllianceGenome:ZFIN:ZDB-GENE-010413-1
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    TRAPb; TRAP[b]; zgc:92180; wu:fb75b04
    Summary
    Predicted to be located in endoplasmic reticulum membrane. Orthologous to human SSR2 (signal sequence receptor subunit 2). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See ssr2 in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 19 NC_007130.7 (11231083..11238721, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 19 NC_007130.6 (11313085..11320723, complement)

    Chromosome 19 - NC_007130.7Genomic Context describing neighboring genes Neighboring gene si:dkey-240h12.4 Neighboring gene si:ch73-109i22.2 Neighboring gene interferon-inducible GTPase 5-like Neighboring gene immunity-related GTPase family, f3 Neighboring gene si:ch73-171o20.1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. The Translocon-Associated Protein beta (TRAPbeta) in zebrafish embryogenesis. I. Enhanced expression of transcripts in notochord and hatching gland precursors. Mangos S, et al. Mol Cell Biochem, 2000 Dec. PMID 11204460
    2. Identification of Novel Reference Genes Suitable for qRT-PCR Normalization with Respect to the Zebrafish Developmental Stage. Hu Y, et al. PLoS One, 2016. PMID 26891128, Free PMC Article
    3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Component Evidence Code Pubs
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    translocon-associated protein subunit beta
    Names
    translocon-associated protein beta

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001001399.2 → NP_001001399.2  translocon-associated protein subunit beta precursor

      Status: VALIDATED

      Source sequence(s)
      BC075915, EH445458, FP074861
      UniProtKB/TrEMBL
      A0A0R4IEM9, A0A8M1MZK6, F8W477, Q6DHQ2
      Related
      ENSDARP00000123966.1, ENSDART00000149169.3
      Conserved Domains (2) summary
      pfam05753
      Location:9 → 182
      TRAP_beta; Translocon-associated protein beta (TRAPB)
      cl14643
      Location:87 → 168
      SRPBCC; START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007130.7 Reference GRCz11 Primary Assembly

      Range
      11231083..11238721 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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