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    GRM5 glutamate metabotropic receptor 5 [ Calidris pugnax (ruff) ]

    Gene ID: 106897607, updated on 3-Aug-2024

    Summary

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    Gene symbol
    GRM5
    Gene description
    glutamate metabotropic receptor 5
    See related
    Ensembl:ENSCPUG00000000953
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Calidris pugnax
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Neoaves; Charadriiformes; Scolopacidae; Calidris
    Orthologs
    human mouse all
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    Genomic context

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    See GRM5 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    100 current ASM143184v1 (GCF_001431845.1) Unplaced Scaffold NW_015091118.1 (2423819..2704693, complement)

    NW_015091118.1Genomic Context describing neighboring genes Neighboring gene RAB38, member RAS oncogene family Neighboring gene cathepsin C Neighboring gene tyrosinase Neighboring gene NADPH oxidase 4

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_015091118.1 Unplaced Scaffold Reference ASM143184v1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables adenylate cyclase inhibiting G protein-coupled glutamate receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in G protein-coupled glutamate receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of synaptic transmission, glutamatergic IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in trans-synaptic signaling by endocannabinoid, modulating synaptic transmission IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in postsynaptic density membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    metabotropic glutamate receptor 5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Calidris pugnax Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ASM143184v1

    Genomic

    1. NW_015091118.1 Reference ASM143184v1

      Range
      2423819..2704693 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_014958370.1 → XP_014813856.1  metabotropic glutamate receptor 5 isoform X1

      Related
      ENSCPUP00000001248.1, ENSCPUT00000001502.1
      Conserved Domains (5) summary
      cd06374
      Location:32 → 503
      PBP1_mGluR_groupI; Ligand binding domain of the group I metabotropic glutamate receptor
      pfam00003
      Location:597 → 830
      7tm_3; 7 transmembrane sweet-taste receptor of 3 GCPR
      pfam01094
      Location:73 → 478
      ANF_receptor; Receptor family ligand binding region
      pfam07562
      Location:514 → 563
      NCD3G; Nine Cysteines Domain of family 3 GPCR
      pfam10606
      Location:1192 → 1242
      GluR_Homer-bdg; Homer-binding domain of metabotropic glutamate receptor

    2. XM_014958369.1 → XP_014813855.1  metabotropic glutamate receptor 5 isoform X1

      Conserved Domains (5) summary
      cd06374
      Location:32 → 503
      PBP1_mGluR_groupI; Ligand binding domain of the group I metabotropic glutamate receptor
      pfam00003
      Location:597 → 830
      7tm_3; 7 transmembrane sweet-taste receptor of 3 GCPR
      pfam01094
      Location:73 → 478
      ANF_receptor; Receptor family ligand binding region
      pfam07562
      Location:514 → 563
      NCD3G; Nine Cysteines Domain of family 3 GPCR
      pfam10606
      Location:1192 → 1242
      GluR_Homer-bdg; Homer-binding domain of metabotropic glutamate receptor

    3. XM_014958372.1 → XP_014813858.1  metabotropic glutamate receptor 5 isoform X3

      Related
      ENSCPUP00000001244.1, ENSCPUT00000001498.1
      Conserved Domains (5) summary
      cd06374
      Location:32 → 503
      PBP1_mGluR_groupI; Ligand binding domain of the group I metabotropic glutamate receptor
      pfam00003
      Location:597 → 830
      7tm_3; 7 transmembrane sweet-taste receptor of 3 GCPR
      pfam01094
      Location:73 → 478
      ANF_receptor; Receptor family ligand binding region
      pfam07562
      Location:514 → 563
      NCD3G; Nine Cysteines Domain of family 3 GPCR
      pfam10606
      Location:1106 → 1156
      GluR_Homer-bdg; Homer-binding domain of metabotropic glutamate receptor

    4. XM_014958371.1 → XP_014813857.1  metabotropic glutamate receptor 5 isoform X2

      Related
      ENSCPUP00000001237.1, ENSCPUT00000001488.1
      Conserved Domains (5) summary
      cd06374
      Location:32 → 503
      PBP1_mGluR_groupI; Ligand binding domain of the group I metabotropic glutamate receptor
      pfam00003
      Location:597 → 830
      7tm_3; 7 transmembrane sweet-taste receptor of 3 GCPR
      pfam01094
      Location:73 → 478
      ANF_receptor; Receptor family ligand binding region
      pfam07562
      Location:514 → 563
      NCD3G; Nine Cysteines Domain of family 3 GPCR
      pfam10606
      Location:1138 → 1188
      GluR_Homer-bdg; Homer-binding domain of metabotropic glutamate receptor
    Nucleotide Protein
    Heading Accession and Version

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