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    PPM1A protein phosphatase, Mg2+/Mn2+ dependent 1A [ Gallus gallus (chicken) ]

    Gene ID: 423525, updated on 3-Dec-2024

    Summary

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    Symbol
    PPM1Aprovided by CGNC
    Full Name
    protein phosphatase, Mg2+/Mn2+ dependent 1Aprovided by CGNC
    Primary source
    CGNC:9036
    See related
    Ensembl:ENSGALG00010016903
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See PPM1A in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 5 NC_052536.1 (54014859..54047791, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 5 NC_052577.1 (54003411..54036358, complement)

    Chromosome 5 - NC_052536.1Genomic Context describing neighboring genes Neighboring gene chromosome 5 open reading frame, human C14orf39 Neighboring gene SIX homeobox 6 Neighboring gene uncharacterized LOC107053579 Neighboring gene dehydrogenase/reductase 7 Neighboring gene pecanex 4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables magnesium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables manganese ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein serine/threonine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of canonical NF-kappaB signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of canonical NF-kappaB signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of canonical Wnt signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein phosphatase 1A
    XP_015143400.1
    XP_015143401.1
    XP_015143402.1
    XP_040529742.1
    XP_040529743.1
    XP_040529744.1
    XP_040529745.1
    XP_040529746.1
    XP_040557561.1
    XP_040557563.1
    XP_046775415.1
    XP_046775416.1
    XP_046798422.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052536.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      54014859..54047791 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040701629.2 → XP_040557563.1  protein phosphatase 1A isoform X2

      UniProtKB/TrEMBL
      A0A8V0Z031, E1BVM8
      Conserved Domains (2) summary
      cd00143
      Location:23 → 291
      PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...
      pfam07830
      Location:285 → 363
      PP2C_C; Protein serine/threonine phosphatase 2C, C-terminal domain

    2. XM_040701627.2 → XP_040557561.1  protein phosphatase 1A isoform X1

      UniProtKB/TrEMBL
      A0A8V0YY86, A0A8V0Z031
      Related
      ENSGALP00010023751.1, ENSGALT00010040787.1
      Conserved Domains (2) summary
      cd00143
      Location:23 → 291
      PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...
      pfam07830
      Location:285 → 363
      PP2C_C; Protein serine/threonine phosphatase 2C, C-terminal domain

    3. XM_015287916.4 → XP_015143402.1  protein phosphatase 1A isoform X3

      UniProtKB/TrEMBL
      A0A8V0Z031
      Conserved Domains (2) summary
      cd00143
      Location:23 → 291
      PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...
      cl29762
      Location:285 → 318
      PP2C_C; Protein serine/threonine phosphatase 2C, C-terminal domain

    4. XM_015287915.4 → XP_015143401.1  protein phosphatase 1A isoform X2

      UniProtKB/TrEMBL
      A0A8V0Z031, E1BVM8
      Related
      ENSGALP00010023753.1, ENSGALT00010040789.1
      Conserved Domains (2) summary
      cd00143
      Location:23 → 291
      PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...
      pfam07830
      Location:285 → 363
      PP2C_C; Protein serine/threonine phosphatase 2C, C-terminal domain

    5. XM_015287914.4 → XP_015143400.1  protein phosphatase 1A isoform X1

      UniProtKB/TrEMBL
      A0A8V0YY86, A0A8V0Z031
      Conserved Domains (2) summary
      cd00143
      Location:23 → 291
      PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...
      pfam07830
      Location:285 → 363
      PP2C_C; Protein serine/threonine phosphatase 2C, C-terminal domain

    6. XM_046942466.1 → XP_046798422.1  protein phosphatase 1A isoform X1

      UniProtKB/TrEMBL
      A0A8V0YY86, A0A8V0Z031

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052577.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      54003411..54036358 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040673811.2 → XP_040529745.1  protein phosphatase 1A isoform X2

      UniProtKB/TrEMBL
      A0A8V0Z031, E1BVM8
      Conserved Domains (2) summary
      cd00143
      Location:23 → 291
      PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...
      pfam07830
      Location:285 → 363
      PP2C_C; Protein serine/threonine phosphatase 2C, C-terminal domain

    2. XM_040673809.2 → XP_040529743.1  protein phosphatase 1A isoform X1

      UniProtKB/TrEMBL
      A0A8V0YY86, A0A8V0Z031
      Conserved Domains (2) summary
      cd00143
      Location:23 → 291
      PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...
      pfam07830
      Location:285 → 363
      PP2C_C; Protein serine/threonine phosphatase 2C, C-terminal domain

    3. XM_040673812.2 → XP_040529746.1  protein phosphatase 1A isoform X3

      UniProtKB/TrEMBL
      A0A8V0Z031
      Conserved Domains (2) summary
      cd00143
      Location:23 → 291
      PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...
      cl29762
      Location:285 → 318
      PP2C_C; Protein serine/threonine phosphatase 2C, C-terminal domain

    4. XM_040673810.2 → XP_040529744.1  protein phosphatase 1A isoform X2

      UniProtKB/TrEMBL
      A0A8V0Z031, E1BVM8
      Conserved Domains (2) summary
      cd00143
      Location:23 → 291
      PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...
      pfam07830
      Location:285 → 363
      PP2C_C; Protein serine/threonine phosphatase 2C, C-terminal domain

    5. XM_040673808.2 → XP_040529742.1  protein phosphatase 1A isoform X1

      UniProtKB/TrEMBL
      A0A8V0YY86, A0A8V0Z031
      Conserved Domains (2) summary
      cd00143
      Location:23 → 291
      PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...
      pfam07830
      Location:285 → 363
      PP2C_C; Protein serine/threonine phosphatase 2C, C-terminal domain

    6. XM_046919460.1 → XP_046775416.1  protein phosphatase 1A isoform X2

      UniProtKB/TrEMBL
      A0A8V0Z031, E1BVM8

    7. XM_046919459.1 → XP_046775415.1  protein phosphatase 1A isoform X1

      UniProtKB/TrEMBL
      A0A8V0YY86, A0A8V0Z031
    Nucleotide Protein
    Heading Accession and Version

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