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    gyrB DNA gyrase subunit B [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948211, updated on 17-Dec-2024

    Summary

    Official Symbol
    gyrB
    Official Full Name
    DNA gyrase subunit B
    Primary source
    ECOCYC:EG10424
    Locus tag
    b3699
    See related
    ASAP:ABE-0012093
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    acrB; Cou; ECK3691; himB; hisU; hopA; nalC; parA; pcbA; pcpA
    Summary
    gyrB is an essential gene. [More information is available at EcoGene: EG10424]. The GyrB subunit of DNA gyrase is required for the ATPase activity of the enzyme. [More information is available at EcoCyc: EG10424].
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    Genomic context

    Sequence:
    NC_000913.3 (3877705..3880119, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene sugar phosphatase YidA Neighboring gene DUF937 domain-containing protein YidB Neighboring gene recombination mediator protein RecF Neighboring gene beta sliding clamp

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables ATP binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables ATP-dependent activity, acting on DNA IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables DNA binding IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    enables DNA negative supercoiling activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables DNA negative supercoiling activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables DNA topoisomerase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in DNA topological change IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in DNA topological change IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within DNA topological change IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in DNA-templated DNA replication IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within DNA-templated transcription IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in chromosome organization IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in response to antibiotic IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within response to xenobiotic stimulus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    part_of DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in chromosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    DNA gyrase subunit B
    YP_026241.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3877705..3880119 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. YP_026241.1 DNA gyrase subunit B [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for YP_026241.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A0H2VCI1, A0A192CEW1, A0A6C9Q9K6, A0AA36L2J9, Q1R4N8
      Conserved Domains (1) summary
      PRK14939
      Location:1804
      gyrB; DNA gyrase subunit B; Provisional